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Funding Update: NIH Grants Awarded to Vanderbilt, Scripps, and More

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NIH Grants in Proteomics, June 19 to August 24, Part 1 of 2 (Part 2 is available here.)

Project Title: Mutation-Specific P53 Antibodies as Biomarkers of Pancreatic Cancer
Contact Principal Investigator: Karen Anderson
Organization Name: Arizona State University-Tempe Campus
Project Start Date: Aug. 8, 2012
Project End Date: July 31, 2014
FY Total Cost: $212,556


Project Title: Development of a Malarial Kinase-on-Phage Screening Platform
Contact Principal Investigator: Clifford Berkman
Organization Name: Washington State University
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2014
FY Total Cost: $218,850


Project Title: Mitochondrial Function in Anesthetic Preconditioning
Contact Principal Investigator: Zeljko Bosnjak
Organization Name: Medical College of Wisconsin
Project Start Date: NA
Project End Date: NA
FY Total Cost: $522,859


Project Title: Center for Polycystic Kidney Disease Research at Yale
Contact Principal Investigator: Michael Caplan
Organization Name: Yale University
Project Start Date: Sept. 30, 2010
Project End Date: June 30, 2015
FY Total Cost: $1,132,955


Project Title: 15 Tesla Bruker Solarix FT-ICR Mass Spectrometer
Contact Principal Investigator: Richard Caprioli
Organization Name: Vanderbilt University
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2013
FY Total Cost: $1,596,640


Project Title: Probing the Role of Cysteine Sulfenylation in Cell Signaling
Contact Principal Investigator: Kate Carroll
Organization Name: Scripps Florida
Project Start Date: Aug. 1, 2012
Project End Date: April 30, 2016
FY Total Cost: $398,293


Project Title: Global Analysis of Cellular Networks Involved in Restriction of HIV Replication
Contact Principal Investigator: Sumit Chanda
Organization Name: Salk Institute for Biological Studies
Project Start Date: NA
Project End Date: NA
FY Total Cost: $943,141


Project Title: An Immunomics Approach to Explore Drug-Induced Resistance to Schistosomes
Contact Principal Investigator: Rodrigo Correa-Oliveira
Organization Name: Foundation for Research Development
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2017
FY Total Cost: $92,422


Project Title: Modeling Drug Induced Resistance in S. mansoni Endemic Areas
Contact Principal Investigator: Rodrigo Correa-Oliveira
Organization Name: Foundation for Research Development
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2017
FY Total Cost: $269,804


Project Title: LTQ Orbitrap Velos
Contact Principal Investigator: Larry David
Organization Name: Oregon Health and Science University
Project Start Date: Aug.1, 2012
Project End Date: July 31, 2013
FY Total Cost: $853,719


Project Title: Targeted Microbubble Contrast-Enhanced Ultrasound Imaging of the Ovarian Cancer
Contact Principal Investigator: Charles Drescher
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $272,565


Project Title: Proteomics
Contact Principal Investigator: Dean Edwards
Organization Name: Baylor College of Medicine
Project Start Date: NA
Project End Date: NA
FY Total Cost: $146,980


Project Title: Protective Biomarkers for the Development of Vaccines Against Malaria
Contact Principal Investigator: Philip Felgner
Organization Name: Immport Therapeutics
Project Start Date: July 15, 2005
Project End Date: July 31, 2015
FY Total Cost: $781,909


Project Title: Analysis of Protein-Ligand Binding on the Proteomic Scale
Contact Principal Investigator: Michael Fitzgerald
Organization Name: Duke University
Project Start Date: Aug. 1, 2009
Project End Date: July 31, 2013
FY Total Cost: $321,081


Project Title: Bioanalytical Chemistry Core B: Innate Reponses to Microbial Infection
Contact Principal Investigator: Bradford Gibson
Organization Name: University of Iowa
Project Start Date: NA
Project End Date: NA
FY Total Cost: $428,919


Project Title: Reverse Vaccinology of Enterotoxigenic E. Coli
Contact Principal Investigator: Philip Hardwidge
Organization Name: University of Kansas Medical Center
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2014
FY Total Cost: $188,750


Project Title: Effector and Regulatory Activities of HLA-E-Restricted HIV-Specific AbCD8 T Cells
Contact Principal Investigator: June Kan-Mitchell
Organization Name: University of Texas El Paso
Project Start Date: Aug. 1, 2012
Project End Date: June 30, 2016
FY Total Cost: $531,600


Project Title: Diabetes and Anesthetic Preconditioning
Contact Principal Investigator: Judy Kersten
Organization Name: Medical College of Wisconsin
Project Start Date: NA
Project End Date: NA
FY Total Cost: $399,159


Project Title: Cell Cycle Proteomics in Xenopus
Contact Principal Investigator: Marc Kirschner
Organization Name: Harvard University Medical School
Project Start Date: Aug. 15, 2012
Project End Date: June 30, 2016
FY Total Cost: $490,530


Project Title: Biomarker Discovery for Early Detection of Pancreatic Ductal Adenocarcinoma
Contact Principal Investigator: Christopher Klug
Organization Name: University of Alabama at Birmingham
Project Start Date: NA
Project End Date: NA
FY Total Cost: $608,037


Project Title: Mass Spectrometry Imaging of Protein Gels
Contact Principal Investigator: Joseph Loo
Organization Name: University of California Los Angeles
Project Start Date: July 23, 2012
Project End Date: April 30, 2016
FY Total Cost: $295,690


Project Title: Aberrantly Secreted Glycoproteins as Markers of Liver Cancer
Contact Principal Investigator: Anand Mehta
Organization Name: Drexel University
Project Start Date: Aug. 8, 2012
Project End Date: June 30, 2017
FY Total Cost: $293,548


Project Title: P-1: Molecular Signatures for Individualizing Lung Cancer Therapy
Contact Principal Investigator: John Minna
Organization Name: University of Texas Southwestern Medical Center/Dallas
Project Start Date: NA
Project End Date: NA
FY Total Cost: $261,985


Project Title: Broadband Ultrasensitive Detector for FT-ICR Mass Spectrometers
Contact Principal Investigator: Alexander Misharin
Organization Name: Masstech
Project Start Date: Aug. 10, 2012
Project End Date: Feb. 9, 2013
FY Total Cost: $166,867


Project Title: Fast Fragmentation Method for Characterization of Peptides With Labile PTMs
Contact Principal Investigator: Eugene Moskovets
Organization Name: Masstech
Project Start Date: Aug. 10, 2012
Project End Date: Aug. 9, 2013
FY Total Cost: $413,605

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.