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Funding Update: NIH Grants Awarded to Vanderbilt, Prognosys Biosciences, and More

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NIH Grants in Proteomics, Oct. 25 to May 1, Part 1 of 3 (Click for part 2 and part 3.)

Project Title: Novel Locations; Familiar Functions: Obscurin at the Cardiac Intercalated Disc
Contact Principal Investigator: Maegen Ackermann
Organization Name: University of Maryland Baltimore
Project Start Date: Feb. 5, 2013
Project End Date: Jan. 31, 2015
FY Total Cost: $129,060


Project Title: CLK Kinases and Splicing Regulation
Contact Principal Investigator: Joseph Adams
Organization Name: University of California San Diego
Project Start Date: June 1, 2012
Project End Date: March 31, 2016
FY Total Cost: $294,500


Project Title: Induced Pluripotent Stem Cells for the Study of Long QT Syndrome
Contact Principal Investigator: Eric Adler
Organization Name: University of California San Diego
Project Start Date: April 18, 2011
Project End Date: March 31, 2016
FY Total Cost: $133,650


Project Title: Global Protein Palmitoylation and DHCC Proteins in T Cell Activation and Anergy
Contact Principal Investigator: Amnon Altman
Organization Name: La Jolla Institute For Allergy & Immunology
Project Start Date: Dec. 1, 2011
Project End Date: Nov. 30, 2016
FY Total Cost: $401,400


Project Title: Human Transcription Factor Immunogens: Generation of a Complete Set
Contact Principal Investigator: Stephen Anderson,
Organization Name: Rutgers, The State University Of New Jersey
Project Start Date: Sept. 23, 2010
Project End Date: Aug. 31, 2014
FY Total Cost: $850,000


Project Title: Lysine Acetylation in N. Gonorrhoeae Quorum Sensing and Biofilm Formation
Contact Principal Investigator: Michael Apicella
Organization Name: University of Iowa
Project Start Date: March 5, 2014
Project End Date: Feb. 28, 2019
FY Total Cost: $831,215


Project Title: Scabies: Biology, Culture, Host Specificity and Antigens
Contact Principal Investigator: Larry Arlian
Organization Name: Wright State University
Project Start Date: Aug. 1, 1981
Project End Date: Feb. 28, 2017
FY Total Cost: $328,500


Project Title: Leukemia Stem Cell Antigen Discovery Using Advanced Genomic and Proteomic Methods
Contact Principal Investigator: Paul Armistead
Organization Name: University of North Carolina Chapel Hill
Project Start Date: May 1, 2012
Project End Date: Feb. 28, 2015
FY Total Cost: $132,088


Project Title: Quantitating Mitophagy in Skeletal Muscle Models
Contact Principal Investigator: Edgar Arriaga
Organization Name: University of Minnesota
Project Start Date: April 15, 2002
Project End Date: March 31, 2016
FY Total Cost: $343,851


Project Title: Isolation of Recycling Synaptic Vesicles for Proteomic Analyses
Contact Principal Investigator: Sandra Bajjalieh
Organization Name: University of Washington
Project Start Date: Dec. 1, 2012
Project End Date: Nov. 30, 2014
FY Total Cost: $173,813


Project Title: Caveolae, T-Type Calcium Channels and Cardiac Hypertrophy
Contact Principal Investigator: Ravi Balijepalli
Organization Name: University of Wisconsin-Madison
Project Start Date: Jan. 15, 2012
Project End Date: Dec. 31, 2016
FY Total Cost: $368,725


Project Title: Docking the Proteome for New Ligands and Functional Associations
Contact Principal Investigator: Trent Balius
Organization Name: University of Toronto
Project Start Date: Jan. 1, 2014
Project End Date: Dec. 31, 2015
FY Total Cost: $51,530


Project Title: MRNA-Binding Proteome in Trypanosoma Brucei
Contact Principal Investigator: Vivian Bellofatto
Organization Name: Rutgers Biomedical and Health Sciences-New Jersey Medical School
Project Start Date: Feb. 1, 2014
Project End Date: Jan. 31, 2016
FY Total Cost: $214,650


Project Title: Vanderbilt Network Lead Academic Participating Site for the NCTN
Contact Principal Investigator: Jordan Berlin
Organization Name: Vanderbilt University
Project Start Date: April 17, 2014
Project End Date: Feb. 28, 2019
FY Total Cost: $587,562


Project Title: Molecular and Cellular Basis of Obesity Core
Contact Principal Investigator: David Bernlohr
Organization Name: University of Minnesota
Project Start Date: NA
Project End Date: NA
FY Total Cost: $261,776


Project Title: Imaging Mass Spectrometry Research Resource at Vanderbilt University
Contact Principal Investigator: Richard Caprioli
Organization Name: Vanderbilt University
Project Start Date: Feb. 15, 2011
Project End Date: Dec. 31, 2015
FY Total Cost: $1,723,507


Project Title: Impact of Pregnancy on Drug Absorption, Disposition and End Organ Response
Contact Principal Investigator: Steve Caritis
Organization Name: Magee-Women's Research Institute and Foundation
Project Start Date: July 1, 2004
Project End Date: Dec. 31, 2014
FY Total Cost: $937,295


Project Title: Multiplexed Protein Assays
Contact Principal Investigator: Mark Chee
Organization Name: Prognosys Biosciences
Project Start Date: April 15, 2014
Project End Date: Feb. 29, 2016
FY Total Cost: $350,000


Project Title: Latent Dirichlet Allocation for Protein Inference in Quantitative Proteomics
Contact Principal Investigator: Aaron Cohen
Organization Name: Oregon Health & Science University
Project Start Date: Jan. 1, 2014
Project End Date: Dec. 31, 2015
FY Total Cost: $200,970


Project Title: Molecular and Cellular Biochemistry Core
Contact Principal Investigator: David Cohen
Organization Name: Children's Hospital Corporation
Project Start Date: NA
Project End Date: NA
FY Total Cost: $175,645


Project Title: Sequential Ion/Ion Reactions for Large Peptide and Whole Protein Characterization
Contact Principal Investigator: Joshua Coon
Organization Name: University of Wisconsin-Madison
Project Start Date: March 1, 2007
Project End Date: Feb. 29, 2016
FY Total Cost: $337,302


Project Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 1997
Project End Date: Dec. 31, 2014
FY Total Cost: $4,388,012


Project Title: Proteomic Biomarkers for AMD
Contact Principal Investigator: John Crabb
Organization Name: Cleveland Clinic Lerner College of Medicine-CWRU
Project Start Date: Dec. 1, 2012
Project End Date: Nov. 30, 2014
FY Total Cost: $192,325


Project Title: Chemical Probes for Metabolic Pathway Discovery in Human Disease
Contact Principal Investigator: Benjamin Cravatt
Organization Name: Scripps Research Institute
Project Start Date: Sep. 24, 2007
Project End Date: Nov. 30, 2018
FY Total Cost: $491,691


Project Title: The Role of the PI3K-Akt Pathway in Melanoma Brain Metastasis
Contact Principal Investigator: Michael Davies
Organization Name: UT MD Anderson Cancer Center
Project Start Date: Feb. 9, 2011
Project End Date: Jan. 31, 2016
FY Total Cost: $295,065


Project Title: The Cell Biology of Coronavirus Infection
Contact Principal Investigator: Mark Denison
Organization Name: Vanderbilt University
Project Start Date: July 1, 2001
Project End Date: Nov. 30, 2014
FY Total Cost: $312,741


Project Title: Functional Proteomics Reverse Phase Protein Array Core
Contact Principal Investigator: Ronald Depinho
Organization Name: UT MD Anderson Cancer Center
Project Start Date: Sep. 4, 1998
Project End Date: June 30, 2018
FY Total Cost: $309,415


Project Title: Developmental Funds
Contact Principal Investigator: Ronald Depinho
Organization Name: UT MD Anderson Cancer Center
Project Start Date: Sep. 4, 1998
Project End Date: June 30, 2018
FY Total Cost: $913,545


Project Title: Role of CSN in the Activity and Dynamic Cycling of Cullin-Ring Ubiquitin Ligases
Contact Principal Investigator: Raymond Deshaies
Organization Name: California Institute of Technology
Project Start Date: Jan. 1, 2013
Project End Date: Dec. 31, 2017
FY Total Cost: $317,896


Project Title: Development of Trans Proteomic Pipeline, an Analysis Suite for Mass Spectrometry
Contact Principal Investigator: Eric Deutsch
Organization Name: Institute for Systems Biology
Project Start Date: April 1, 2009
Project End Date: March 31, 2018
FY Total Cost: $521,297


Project Title: Colistin-Resistant Acinetobacter Baumannii
Contact Principal Investigator: Yohei Doi
Organization Name: University of Pittsburgh
Project Start Date: March 15, 2014
Project End Date: Feb. 28, 2019
FY Total Cost: $374,839


Project Title: Research Support Core B: Multiscale Imaging and Proteomics Core
Contact Principal Investigator: Mark Ellisman
Organization Name: University of California San Diego
Project Start Date: NA
Project End Date: NA
FY Total Cost: $175,431


Project Title: Global Characterization of Protein Palmitoylation in Trypanosomes
Contact Principal Investigator: David Engman
Organization Name: Northwestern University Chicago
Project Start Date: July 1, 2013
Project End Date: March 31, 2017
FY Total Cost: $366,633


Project Title: Protein Biomarkers for Invasive Aspergillosis Diagnostics
Contact Principal Investigator: Marta Feldmesser
Organization Name: Albert Einstein College of Medicine
Project Start Date: Jan. 1, 2010
Project End Date: Feb. 28, 2015
FY Total Cost: $450,509


Project Title: Ubiquitinated Proteins in Exosomes of Immune Suppressive Myeloid Cells
Contact Principal Investigator: Catherine Fenselau
Organization Name: University of Maryland College Park Campus
Project Start Date: July 1, 1987
Project End Date: Jan. 31, 2018
FY Total Cost: $375,608


Project Title: Regulation on of the AIRAP/aip-1 Pathway by Metabolic Stress
Contact Principal Investigator: Alfred Fisher
Organization Name: University of Texas Health Science Center, San Antonio
Project Start Date: Aug. 1, 2013
Project End Date: March 31, 2015
FY Total Cost: $230,776


Project Title: Functional Glycomics of Human Saliva
Contact Principal Investigator: Susan Fisher
Organization Name: University of California, San Francisco
Project Start Date: April 1, 2011
Project End Date: March 31, 2016
FY Total Cost: $386,250


Project Title: Predictive Biomarkers for EAE Development
Contact Principal Investigator: Thomas Forsthuber
Organization Name: University Of Texas San Antonio
Project Start Date: March 1, 2014
Project End Date: Feb. 29, 2016
FY Total Cost: $220,500


Project Title: Proteomics Shared Resource
Contact Principal Investigator: Scott Gerber
Organization Name: Dartmouth College
Project Start Date: NA
Project End Date: NA
FY Total Cost: $53,938


Project Title: Development and Commercialization of Ocular Diagnostic Test Based on Vitreous Pro
Contact Principal Investigator: Bert Glaser
Organization Name: Ocular Proteomics
Project Start Date: Sep. 1, 2010
Project End Date: March 31, 2015
FY Total Cost: $484,296


Project Title: Regulation of Signaling Receptor Activity by LRP-1
Contact Principal Investigator: Steven Gonias
Organization Name: University of California San Diego
Project Start Date: Aug. 1, 1999
Project End Date: Dec. 31, 2014
FY Total Cost: $374,740


Project Title: Mechanisms of Action of the SMYD3 Methyltransferase in Cancer Cells
Contact Principal Investigator: Or Gozani
Organization Name: Stanford University
Project Start Date: Jan. 1, 2013
Project End Date: Dec. 31, 2017
FY Total Cost: $411,756


Project Title: Function of PHD Domain Proteins in Chromatin Regulation
Contact Principal Investigator: Or Gozani
Organization Name: Stanford University
Project Start Date: March 1, 2007
Project End Date: Dec. 31, 2016
FY Total Cost: $314,000


Project Title: Proteomics Core Facility
Contact Principal Investigator: Lee Graves
Organization Name: University of North Carolina Chapel Hill
Project Start Date: NA
Project End Date: NA
FY Total Cost: $202,670


Project Title: Model-Based Predictions of Responses RTK Pathway Therapies
Contact Principal Investigator: Joe Gray
Organization Name: Oregon Health & Science University
Project Start Date: Sep. 30, 2004
Project End Date: Feb. 28, 2015
FY Total Cost: $2,068,954

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.