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Funding Update: NIH Grants Awarded to Scripps, MD Anderson, and More

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NIH Grants in Proteomics, January 3 to February 7

Project Title: Role of O-GlcNAc in Human Embryonic Stem Cell Pluripotency and Differentiation
Contact Principal Investigator: Lissette Andres
Organization Name: University of California Berkeley
Project Start Date: Feb. 1, 2011
Project End Date: July 31, 2013
FY Total Cost: $22,758


Project Title: Reconstructing Targetable Pathways in Lung Cancer Using a Bioinformatics Approach
Contact Principal Investigator: Oscar Balbin
Organization Name: University of Michigan at Ann Arbor
Project Start Date: Jan. 1, 2012
Project End Date: Dec. 31, 2013
FY Total Cost: $32,419


Project Title: Caveolae, T-Type Calcium Channels and Cardiac Hypertrophy
Contact Principal Investigator: Ravi Balijepalli
Organization Name: University of Wisconsin-Madison
Project Start Date: Jan. 15, 2012
Project End Date: Dec. 31, 2016
FY Total Cost: $338,625


Project Title: Investigations of Bacterial Biofilm Proteomes Using Artifical Amino Acids
Contact Principal Investigator: Nicholas Ball
Organization Name: California Institute of Technology
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2014
FY Total Cost: $52,190


Project Title: Phosphoproteome of Toxoplasma
Contact Principal Investigator: John Boothroyd
Organization Name: Stanford University
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2014
FY Total Cost: $195,490


Project Title: Study of Transmissible Forms of Vibrio Cholerae
Contact Principal Investigator: Andrew Camilli
Organization Name: Tufts University Boston
Project Start Date: May 15, 2003
Project End Date: Jan. 31, 2014
FY Total Cost: $363,863


Project Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 1997
Project End Date: Dec. 31, 2013
FY Total Cost: $58,494


Project Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 1997
Project End Date: Dec. 31, 2013
FY Total Cost: $5,214,516


Project Title: The Role of the PI3K-Akt Pathway in Melanoma Brain Metastasis
Contact Principal Investigator: Michael Davies
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: Feb. 9, 2011
Project End Date: Jan. 31, 2016
FY Total Cost: $147,533


Project Title: HIV 1 NEF and Viral Infectivity
Contact Principal Investigator: John Guatelli,
Organization Name: Veterans Medical Research Foundation/San Diego
Project Start Date: Aug. 15, 1996
Project End Date: Jan. 31, 2014
FY Total Cost: $340,797


Project Title: Nanotechnology Enabled Top-Down Phosphoproteomics
Contact Principal Investigator: Song Jin,
Organization Name: University of Wisconsin-Madison
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2014
FY Total Cost: $199,539


Project Title: Molecular Mechanisms Linking Aging, A-beta Proteotoxicity and Neurodegeneration
Contact Principal Investigator: Jeffery Kelly
Organization Name: Scripps Research Institute
Project Start Date: Feb. 1, 2009
Project End Date: Jan. 31, 2014
FY Total Cost: $1,760,830


Project Title: Stress Signaling Pathways and Resistance in Colorectal Cancer
Contact Principal Investigator: Scott Kopetz
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: Jan. 18, 2013
Project End Date: Dec. 31, 2017
FY Total Cost: $237,082


Project Title: Modification of Host Proteins During Chlamydia Infection
Contact Principal Investigator: Christine Mcbeth,
Organization Name: Harvard University Medical School
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2015
FY Total Cost: $53,942


Project Title: Revealing the HIV-1 Interactome
Contact Principal Investigator: Mark Muesing
Organization Name: Aaron Diamond AIDS Research Center
Project Start Date: Feb. 15, 2009
Project End Date: Jan. 31, 2014
FY Total Cost: $402,454


Project Title: Targeting and Trafficking of 5-HT2A Serotonin Receptors
Contact Principal Investigator: Bryan Roth
Organization Name: University of North Carolina Chapel Hill
Project Start Date: Sept. 1, 2000
Project End Date: Jan. 31, 2015
FY Total Cost: $327,104


Project Title: Functions of the Mitochondrial Proteome: An Integrated Multi-Species Approach
Contact Principal Investigator: Jared Rutter
Organization Name: University of Utah
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $268,575


Project Title: Manipulation of Host Cell Acetylome in AIDS Opportunistic Infection
Contact Principal Investigator: William Sullivan
Organization Name: Indiana University-Purdue University at Indianapolis
Project Start Date: Jan. 15, 2013
Project End Date: Dec. 31, 2014
FY Total Cost: $195,000


Project Title: Dynamics of Cardiac Nuclei in Heart Disease
Contact Principal Investigator: Thomas Vondriska
Organization Name: University of California Los Angeles
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2015
FY Total Cost: $346,500


Project Title: Structure, Function and Inhibition of Human O-GlcNAc Transferase
Contact Principal Investigator: Suzanne Walker
Organization Name: Harvard University Medical School
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $465,154


Project Title: Submicrometer Silica Particles for High-Throughput Separations of Protein Pharmaceuticals
Contact Principal Investigator: Mary Wirth
Organization Name: Purdue University West Lafayette
Project Start Date: April 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $250,544


Project Title: Regulation of Extracellular Chaperone Capacity by the Unfolded Protein Response
Contact Principal Investigator: Rockland Wiseman
Organization Name: Scripps Research Institute
Project Start Date: Feb. 1, 2013
Project End Date: Jan. 31, 2015
FY Total Cost: $236,875


Project Title: Gene Expression in Stage-Specific Populations of Rickettsia Prowazekii
Contact Principal Investigator: David Wood
Organization Name: University of South Alabama
Project Start Date: Jan. 18, 2013
Project End Date: Dec. 31, 2014
FY Total Cost: $222,750


Project Title: Proteomics
Contact Principal Investigator: John Yates
Organization Name: Scripps Research Institute
Project Start Date: NA
Project End Date: NA
FY Total Cost: $376,264


Project Title: Towards a Comprehensive Protein Interactome Network in Schizosaccharomyces Pombe
Contact Principal Investigator: Haiyuan Yu
Organization Name: Cornell University
Project Start Date: May 1, 2012
Project End Date: Jan. 31, 2017
FY Total Cost: $335,427


Project Title: Chlamydia Trachomatis Proteomics
Contact Principal Investigator: Guangming Zhong
Organization Name: University of Texas Health Science Center, San Antonio
Project Start Date: April 1, 2005
Project End Date: Dec. 31, 2015
FY Total Cost: $334,125

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.