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Funding Update: NIH Grants Awarded to Scripps, MD Anderson, and More

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NIH Grants in Proteomics, January 3 to February 7

Project Title: Role of O-GlcNAc in Human Embryonic Stem Cell Pluripotency and Differentiation
Contact Principal Investigator: Lissette Andres
Organization Name: University of California Berkeley
Project Start Date: Feb. 1, 2011
Project End Date: July 31, 2013
FY Total Cost: $22,758


Project Title: Reconstructing Targetable Pathways in Lung Cancer Using a Bioinformatics Approach
Contact Principal Investigator: Oscar Balbin
Organization Name: University of Michigan at Ann Arbor
Project Start Date: Jan. 1, 2012
Project End Date: Dec. 31, 2013
FY Total Cost: $32,419


Project Title: Caveolae, T-Type Calcium Channels and Cardiac Hypertrophy
Contact Principal Investigator: Ravi Balijepalli
Organization Name: University of Wisconsin-Madison
Project Start Date: Jan. 15, 2012
Project End Date: Dec. 31, 2016
FY Total Cost: $338,625


Project Title: Investigations of Bacterial Biofilm Proteomes Using Artifical Amino Acids
Contact Principal Investigator: Nicholas Ball
Organization Name: California Institute of Technology
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2014
FY Total Cost: $52,190


Project Title: Phosphoproteome of Toxoplasma
Contact Principal Investigator: John Boothroyd
Organization Name: Stanford University
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2014
FY Total Cost: $195,490


Project Title: Study of Transmissible Forms of Vibrio Cholerae
Contact Principal Investigator: Andrew Camilli
Organization Name: Tufts University Boston
Project Start Date: May 15, 2003
Project End Date: Jan. 31, 2014
FY Total Cost: $363,863


Project Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 1997
Project End Date: Dec. 31, 2013
FY Total Cost: $58,494


Project Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization Name: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 1997
Project End Date: Dec. 31, 2013
FY Total Cost: $5,214,516


Project Title: The Role of the PI3K-Akt Pathway in Melanoma Brain Metastasis
Contact Principal Investigator: Michael Davies
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: Feb. 9, 2011
Project End Date: Jan. 31, 2016
FY Total Cost: $147,533


Project Title: HIV 1 NEF and Viral Infectivity
Contact Principal Investigator: John Guatelli,
Organization Name: Veterans Medical Research Foundation/San Diego
Project Start Date: Aug. 15, 1996
Project End Date: Jan. 31, 2014
FY Total Cost: $340,797


Project Title: Nanotechnology Enabled Top-Down Phosphoproteomics
Contact Principal Investigator: Song Jin,
Organization Name: University of Wisconsin-Madison
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2014
FY Total Cost: $199,539


Project Title: Molecular Mechanisms Linking Aging, A-beta Proteotoxicity and Neurodegeneration
Contact Principal Investigator: Jeffery Kelly
Organization Name: Scripps Research Institute
Project Start Date: Feb. 1, 2009
Project End Date: Jan. 31, 2014
FY Total Cost: $1,760,830


Project Title: Stress Signaling Pathways and Resistance in Colorectal Cancer
Contact Principal Investigator: Scott Kopetz
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: Jan. 18, 2013
Project End Date: Dec. 31, 2017
FY Total Cost: $237,082


Project Title: Modification of Host Proteins During Chlamydia Infection
Contact Principal Investigator: Christine Mcbeth,
Organization Name: Harvard University Medical School
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2015
FY Total Cost: $53,942


Project Title: Revealing the HIV-1 Interactome
Contact Principal Investigator: Mark Muesing
Organization Name: Aaron Diamond AIDS Research Center
Project Start Date: Feb. 15, 2009
Project End Date: Jan. 31, 2014
FY Total Cost: $402,454


Project Title: Targeting and Trafficking of 5-HT2A Serotonin Receptors
Contact Principal Investigator: Bryan Roth
Organization Name: University of North Carolina Chapel Hill
Project Start Date: Sept. 1, 2000
Project End Date: Jan. 31, 2015
FY Total Cost: $327,104


Project Title: Functions of the Mitochondrial Proteome: An Integrated Multi-Species Approach
Contact Principal Investigator: Jared Rutter
Organization Name: University of Utah
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $268,575


Project Title: Manipulation of Host Cell Acetylome in AIDS Opportunistic Infection
Contact Principal Investigator: William Sullivan
Organization Name: Indiana University-Purdue University at Indianapolis
Project Start Date: Jan. 15, 2013
Project End Date: Dec. 31, 2014
FY Total Cost: $195,000


Project Title: Dynamics of Cardiac Nuclei in Heart Disease
Contact Principal Investigator: Thomas Vondriska
Organization Name: University of California Los Angeles
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2015
FY Total Cost: $346,500


Project Title: Structure, Function and Inhibition of Human O-GlcNAc Transferase
Contact Principal Investigator: Suzanne Walker
Organization Name: Harvard University Medical School
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $465,154


Project Title: Submicrometer Silica Particles for High-Throughput Separations of Protein Pharmaceuticals
Contact Principal Investigator: Mary Wirth
Organization Name: Purdue University West Lafayette
Project Start Date: April 1, 2012
Project End Date: Jan. 31, 2016
FY Total Cost: $250,544


Project Title: Regulation of Extracellular Chaperone Capacity by the Unfolded Protein Response
Contact Principal Investigator: Rockland Wiseman
Organization Name: Scripps Research Institute
Project Start Date: Feb. 1, 2013
Project End Date: Jan. 31, 2015
FY Total Cost: $236,875


Project Title: Gene Expression in Stage-Specific Populations of Rickettsia Prowazekii
Contact Principal Investigator: David Wood
Organization Name: University of South Alabama
Project Start Date: Jan. 18, 2013
Project End Date: Dec. 31, 2014
FY Total Cost: $222,750


Project Title: Proteomics
Contact Principal Investigator: John Yates
Organization Name: Scripps Research Institute
Project Start Date: NA
Project End Date: NA
FY Total Cost: $376,264


Project Title: Towards a Comprehensive Protein Interactome Network in Schizosaccharomyces Pombe
Contact Principal Investigator: Haiyuan Yu
Organization Name: Cornell University
Project Start Date: May 1, 2012
Project End Date: Jan. 31, 2017
FY Total Cost: $335,427


Project Title: Chlamydia Trachomatis Proteomics
Contact Principal Investigator: Guangming Zhong
Organization Name: University of Texas Health Science Center, San Antonio
Project Start Date: April 1, 2005
Project End Date: Dec. 31, 2015
FY Total Cost: $334,125

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.