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Funding Update: NIH Grants Awarded to Dana-Farber, Vanderbilt, and More

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NIH Grants in Proteomics, June 18 to July 25, Part 2 of 2 (Part 1 is available here.)

Project Title: Vaccine Development for Falciparum Malaria in Pregnant Women and Their Offspring
Contact Principal Investigator: Ian Michelow
Organization Name: Rhode Island Hospital
Project Start Date: July 1, 2013
Project End Date: June 30, 2018
FY Total Cost: $155,064


Project Title: A Novel Multiplexed Assay for Rapid Antibody Screening
Contact Principal Investigator: Scott Monsma
Organization Name: Primorigen Biosciences
Project Start Date: Sept. 1, 2008
Project End Date: June 30, 2014
FY Total Cost: $381,484


Project Title: Lmf1 in Lapse Expression and Lipid Metabolism
Contact Principal Investigator: Miklos Peterfy
Organization Name:University of California Los Angeles
Project Start Date: NA
Project End Date: NA
FY Total Cost: $411,235


Project Title: Development of a Point-Of-Care Volumetric Bar-Chart Chip for Drug Quantitation
Contact Principal Investigator: Lidong Qin
Organization Name: Methodist Hospital Research Institute
Project Start Date: July 15, 2013
Project End Date: May 31, 2016
FY Total Cost: $707,871


Project Title: Crossprotective CTL Against Influenza
Contact Principal Investigator: Ellis Reinherz
Organization Name: Dana-Farber Cancer Institute
Project Start Date: July 12, 2010
Project End Date: June 30, 2015
FY Total Cost: $1,108,246


Project Title: Mass Spectrometry Core
Contact Principal Investigator: Jackson Roberts
Organization Name: Vanderbilt University Medical Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $65,115


Project Title: Administrative & Biostatistics Core
Contact Principal Investigator: Jackson Roberts
Organization Name: Vanderbilt University Medical Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $65,151


Project Title: RANK-RANKL and Vascular Complications in Chronic Kidney Disease
Contact Principal Investigator: Michael Rosenfeld
Organization Name: University of Washington
Project Start Date: Aug. 15, 2012
Project End Date: June 30, 2017
FY Total Cost: $484,957


Project Title: Epitope Mapping and Prediction
Contact Principal Investigator: Alessandro Sette
Organization Name: Emory University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $246,828


Project Title: Proteomics Resource
Contact Principal Investigator: Lawrence Shapiro
Organization Name: Columbia University Health Sciences
Project Start Date: July 4, 1997
Project End Date: June 30, 2014
FY Total Cost: $136,392


Project Title: Factors Mediating Host Resistance to Chlamydia Trachomatis
Contact Principal Investigator: Michael Starnbach
Organization Name: Harvard University Medical School
Project Start Date: Aug. 1, 2005
Project End Date: June 30, 2015
FY Total Cost: $371,935


Project Title: Acquisition of an Orbitrap Elite Mass Spectrometer with ETD
Contact Principal Investigator: Beatrix Ueberheide
Organization Name: New York University School Of Medicine
Project Start Date: July 1, 2013
Project End Date: June 30, 2014
FY Total Cost: $600,000


Project Title: CRT and Mitochondrial Function and Proteome Post-Translational Modifications
Contact Principal Investigator: Jennifer Van Eyk
Organization Name: Johns Hopkins University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $415,288


Project Title: ESI-TOF Mass Spectrometer for Molecular Mass Analysis: Proteins/Small Molecules
Contact Principal Investigator: Susan Weintraub
Organization Name: University of Texas Health Science Center, San Antonio
Project Start Date: July 19, 2013
Project End Date: July 18, 2014
FY Total Cost: $165,328


Project Title: Regulating Proteolysis to Dissect Apoptosis
Contact Principal Investigator: James Wells
Organization Name: University of California-San Francisco
Project Start Date: Sept. 20, 2011
Project End Date: June 30, 2015
FY Total Cost: $275,452


Project Title: Development of Single Particle Analyzer of Mass and Mobility (SPAMM)
Contact Principal Investigator: Evan Williams
Organization Name: University of California Berkeley
Project Start Date: July 1, 2011
Project End Date: June 30, 2015
FY Total Cost: $221,200


Project Title: CIEF of Glycoproteins in Short Nanoporous Channels
Contact Principal Investigator: Mary Wirth
Organization Name: Purdue University West Lafayette
Project Start Date: July 1, 2012
Project End Date: June 30, 2014
FY Total Cost: $149,618


Project Title: Proteomic and Viral Vector Core (Gygi)
Contact Principal Investigator: Kunhong Xiao
Organization Name: Duke University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $439,871


Project Title: Protein Core
Contact Principal Investigator: Gerard Zurawski
Organization Name: Baylor Research Institute
Project Start Date: NA
Project End Date: NA
FY Total Cost: $230,472

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

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Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.