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Funding Update: NIH Grants Awarded to Columbia, Sonata Biosciences, and More

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NIH Grants in Proteomics, June 26 to Sept. 14, Part 2 of 2 (Click for part 1.)

Project Title: Recognition of Non-Ubiquitin Signals at the Proteasome
Contact Principal Investigator: David Fushman
Organization Name: University of Maryland, College Park
Project Start Date: Sept. 15, 2011
Project End Date: Aug. 31, 2015
FY Total Cost: $346,711


Project Title: Plasma DSC for Early Detection of Disease and Therapeutic Efficacy in Melanoma
Contact Principal Investigator: Nichola Garbett
Organization Name: University of Louisville
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2016
FY Total Cost: $195,750


Project Title: Regulation of the DNA Damage Response by ATM-MRN Pathway
Contact Principal Investigator: Jean Gautier
Organization Name: Columbia University Health Sciences
Project Start Date: July 1, 2001
Project End Date: May 31, 2018
FY Total Cost: $238,295


Project Title: Top Down Proteomics of Myofilaments in Heart Failure
Contact Principal Investigator: Ying Ge
Organization Name: University of Wisconsin-Madison
Project Start Date: Aug. 5, 2011
Project End Date: April 30, 2016
FY Total Cost: $364,765


Project Title: P3 - Personalized Therapy for Low-Grade Serous Carcinoma of the Ovary
Contact Principal Investigator: David Gershenson
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $186,712


Project Title: Bioanalytical Chemistry Core B: Innate Reponses to Microbial Infection
Contact Principal Investigator: Bradford Gibson
Organization Name: University of Iowa
Project Start Date: NA
Project End Date: NA
FY Total Cost: $405,764


Project Title: Modeling a Cellular Protein Homeostasis Network
Contact Principal Investigator: Lila Gierasch
Organization Name: University of Massachusetts Amherst
Project Start Date: Sept. 5, 2013
Project End Date: Aug. 31, 2017
FY Total Cost: $408,725


Project Title: Landscape of Transcription in Human and Mouse
Contact Principal Investigator: Thomas Gingeras
Organization Name: Cold Spring Harbor Laboratory
Project Start Date: Sept. 21, 2012
Project End Date: July 31, 2016
FY Total Cost: $2,079,879


Project Title: Alliance of Glycobiologists for Detection of Cancer
Contact Principal Investigator: Radoslav Goldman
Organization Name: Georgetown University
Project Start Date: Sept. 14, 2012
Project End Date: Aug. 31, 2017
FY Total Cost: $346,619


Project Title: Extrinsic Perturbations of Cell Physiology and Associated Regulatory Networks
Contact Principal Investigator: Joe Gray
Organization Name: Oregon Health & Science University
Project Start Date: Sept. 10, 2014
Project End Date: June 30, 2020
FY Total Cost: $1,714,600


Project Title: Protein Tyrosine Phosphorylation by Dual Specificity Kinases in M. Tuberculosis
Contact Principal Investigator: Christoph Grundner
Organization Name: Seattle Biomedical Research Institute
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2016
FY Total Cost: $296,200


Project Title: Biomolecular and Proteomics Shared Resource
Contact Principal Investigator: David Hachey
Organization Name: Vanderbilt University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $283,319


Project Title: Proteomics of Porphyromonas Gingivalis Interactions with Fusobacterium Nucleatum
Contact Principal Investigator: Murray Hackett
Organization Name: University of Washington
Project Start Date: Jan. 1, 2002
Project End Date: May 31, 2015
FY Total Cost: $274,320


Project Title: Systematic Discovery and Functional Analysis of the Parkinson's Modified Proteome
Contact Principal Investigator: Jeffrey Harper
Organization Name: Harvard Medical School
Project Start Date: Sept. 25, 2013
Project End Date: June 30, 2017
FY Total Cost: $419,513


Project Title: Development of a Non-Destructive Molecular Extraction Platform for Quantitative Proteomics
Contact Principal Investigator: Huiqi He
Organization Name: Bio-Quick Corporation
Project Start Date: Sept. 1, 2014
Project End Date: Feb. 28, 2015
FY Total Cost: $150,000


Project Title: Role of PNPLA3 in Fatty Liver Disease
Contact Principal Investigator: Helen Hobbs
Organization Name: UT Southwestern Medical Center
Project Start Date: Dec. 1, 2010
Project End Date: July 31, 2018
FY Total Cost: $345,825


Project Title: Biomarker Discovery for AO Accumulation in Kidney
Contact Principal Investigator: Eric Hoffman
Organization Name: Children's Research Institute
Project Start Date: NA
Project End Date: NA
FY Total Cost: $99,955


Project Title: Molecular Profiling and Computational Biology (MPCB)
Contact Principal Investigator: King Holmes
Organization Name: University of Washington
Project Start Date: NA
Project End Date: NA
FY Total Cost: $455,681


Project Title: Organ-Specific, Blood Protein Biomarkers for an Informative Diagnosis of Brain
Contact Principal Investigator: Leroy Hood
Organization Name: California Institute of Technology
Project Start Date: NA
Project End Date: NA
FY Total Cost: $664,991


Project Title: Systems Biology Core
Contact Principal Investigator: Leroy Hood
Organization Name: California Institute of Technology
Project Start Date: NA
Project End Date: NA
FY Total Cost: $51,896


Project Title: Biomarkers of Persistent TB Infection and TB Treatment Relapse
Contact Principal Investigator: Robert Horsburgh
Organization Name: Boston Medical Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $437,395


Project Title: Chemical Approaches to Understand the Roles of O-GlcNAc Glycosylation in Biology
Contact Principal Investigator: Linda Hsieh-Wilson
Organization Name: California Institute of Technology
Project Start Date: Dec. 1, 2002
Project End Date: April 30, 2017
FY Total Cost: $409,832


Project Title: The Mechanisms Driving Brain Oncogenesis By FGFR-TACC Gene Fusions
Contact Principal Investigator: Antonio Iavarone
Organization Name: Columbia University Health Sciences
Project Start Date: July 2, 2014
Project End Date: May 31, 2019
FY Total Cost: $375,952


Project Title: Sample Pretreatment for Human Fluids
Contact Principal Investigator: Frank Jahnke
Organization Name: Sonata Biosciences
Project Start Date: Sept. 8, 2014
Project End Date: June 30, 2016
FY Total Cost: $265,864


Project Title: Orbitrap Elite/H-ESI Bundle
Contact Principal Investigator: Dean Jones
Organization Name: Emory University
Project Start Date: July 1, 2014
Project End Date: June 30, 2015
FY Total Cost: $600,000


Project Title: Biomarkers of Neonatal Encephalopathy in a Nonhuman Primate Model
Contact Principal Investigator: Sandra Juul
Organization Name: University of Washington
Project Start Date: Aug. 1, 2013
Project End Date: May 31, 2018
FY Total Cost: $640,177


Project Title: High-Throughput Molecular Profiling Core
Contact Principal Investigator: Michael Katze
Organization Name: University of North Carolina Chapel Hill
Project Start Date: NA
Project End Date: NA
FY Total Cost: $845,786


Project Title: Eukaryotic Post-Translational Modifications
Contact Principal Investigator: Neil Kelleher
Organization Name: Northwestern University
Project Start Date: Aug. 1, 2003
Project End Date: July 31, 2016
FY Total Cost: $328,795


Project Title: High Throughput Mass Spectrometry and Electrophoresis Assay Systems
Contact Principal Investigator: Robert Kennedy
Organization Name: University of Michigan
Project Start Date: Sept. 30, 2012
Project End Date: July 31, 2016
FY Total Cost: $281,468


Project Title: Recombinant Antibodies for Antibody Arrays
Contact Principal Investigator: John Kenten
Organization Name: Meso Scale Diagnostics
Project Start Date: Sept. 1, 2014
Project End Date: Aug. 31, 2015
FY Total Cost: $297,840


Project Title: Airway Mucus/Mucin Composition and Proteome in COPD: A Spiromics Ancillary Study
Contact Principal Investigator: Mehmet Kesimer
Organization Name: University of North Carolina Chapel Hill
Project Start Date: Aug. 22, 2011
Project End Date: June 30, 2015
FY Total Cost: $362,600


Project Title: Biomarker Discovery for Early Detection of Pancreatic Ductal Adenocarcinoma
Contact Principal Investigator: Christopher Klug
Organization Name: University of Alabama at Birmingham
Project Start Date: NA
Project End Date: NA
FY Total Cost: $576,372


Project Title: Disease Determinants of Urban Leptospirosis
Contact Principal Investigator: Albert Ko
Organization Name: Yale University
Project Start Date: Aug. 10, 2010
Project End Date: July 31, 2015
FY Total Cost: $650,100


Project Title: Quantification of Tyrosine Phosphorylation and Kinase Expression in NSCLC
Contact Principal Investigator: John Koomen
Organization Name: H. Lee Moffitt Cancer Center & Research Institute
Project Start Date: July 2, 2013
Project End Date: June 30, 2015
FY Total Cost: $177,747


Project Title: Recombinant Antibody Network
Contact Principal Investigator: Anthony Kossiakoff
Organization Name: University of Chicago
Project Start Date: Sept. 26, 2011
Project End Date: July 31, 2015
FY Total Cost: $1


Project Title: Identifying Non-Histone Targets of the Neural Crest Methyltransferase NSD3
Contact Principal Investigator: Daniel Kretzschmar
Organization Name: University of Minnesota
Project Start Date: Aug. 27, 2013
Project End Date: Aug. 26, 2016
FY Total Cost: $29,600


Project Title: Connecting the Proteome and Transcriptome During Regeneration
Contact Principal Investigator: Kenro Kusumi
Organization Name: Arizona State University-Tempe Campus
Project Start Date: Sept. 1, 2013
Project End Date: Aug. 31, 2015
FY Total Cost: $155,980


Project Title: National Resource for Imaging Mass Spectrometry
Contact Principal Investigator: Claude Lechene
Organization Name: Brigham and Women's Hospital
Project Start Date: Sept. 1, 2003
Project End Date: Feb. 28, 2015
FY Total Cost: $250,000


Project Title: Discovery of Novel Proteomic Targets for Treatment of Alzheimer's Disease
Contact Principal Investigator: Allan Levey
Organization Name: Emory University
Project Start Date: Sept. 1, 2014
Project End Date: April 30, 2019
FY Total Cost: $110,684


Project Title: Elucidation of TUBBY and TULP 1 Mechanisms by Comparitive Functional Proteomics
Contact Principal Investigator: Wei Li
Organization Name: University of Miami School of Medicine
Project Start Date: Sept. 30, 2011
Project End Date: Aug. 31, 2015
FY Total Cost: $261,854


Project Title: Vanderbilt Proteome Characterization Center
Contact Principal Investigator: Daniel Liebler
Organization Name: Vanderbilt University
Project Start Date: Aug. 26, 2011
Project End Date: July 31, 2016
FY Total Cost: $2,744,732


Project Title: Generation and Proteome-Wide Screening of Hybrid Combinatorial Libraries
Contact Principal Investigator: Jun Liu
Organization Name: Johns Hopkins University
Project Start Date: Sept. 30, 2010
Project End Date: July 31, 2015
FY Total Cost: $405,900


Project Title: A Mass Spectrometry System for Quantitative Proteomics
Contact Principal Investigator: Peter Lobel
Organization Name: RBHS-Robert Wood Johnson Medical School
Project Start Date: July 1, 2014
Project End Date: June 30, 2015
FY Total Cost: $561,294


Project Title: High-Resolution Ion Mobility Mass Spectrometer
Contact Principal Investigator: Joseph Loo
Organization Name: University of California Los Angeles
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2015
FY Total Cost: $914,873


Project Title: Biomarkers Core
Contact Principal Investigator: David Loose
Organization Name: University of Texas MD Anderson Cancer Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $215,900


Project Title: Mechanisms of Signal-Induced Alternative Splicing: Cd45
Contact Principal Investigator: Kristen Lynch
Organization Name: University of Pennsylvania
Project Start Date: May 1, 2003
Project End Date: June 30, 2016
FY Total Cost: $334,990


Project Title: Differentiating Ulcerative Colitis and Crohns Colitis Through Proteomic Patterns
Contact Principal Investigator: Amosy M'koma
Organization Name: Meharry Medical College
Project Start Date: Aug. 1, 2013
Project End Date: July 31, 2015
FY Total Cost: $180,534


Project Title: Skyline Targeted Proteomics Environment
Contact Principal Investigator: Michael Maccoss
Organization Name: University of Washington
Project Start Date: Sept. 14, 2011
Project End Date: Aug. 31, 2016
FY Total Cost: $386,250


Project Title: STIM-Dependent Signaling in Cardiac Pathophysiology
Contact Principal Investigator: Salvatore Mancarella
Organization Name: University of Tennessee Health Science Center
Project Start Date: Aug. 2, 2013
Project End Date: July 31, 2015
FY Total Cost: $102,911


Project Title: Partnership for High-Throughput Enabled Biology of the Mitochondrial Proteome
Contact Principal Investigator: John Markley
Organization Name: University of Wisconsin-Madison
Project Start Date: Sept. 30, 2010
Project End Date: June 30, 2015
FY Total Cost: $1,507,706


Project Title: A Nano ESI-LCMS/MS Waters Xevo G2-S QTOF
Contact Principal Investigator: Dwight Matthews
Organization Name: University of Vermont & State Agriculture College
Project Start Date: July 1, 2014
Project End Date: June 30, 2015
FY Total Cost: $461,608


Project Title: Mechanisms and Function Of NFКβ Activation at Dendritic Spines
Contact Principal Investigator: Mollie Meffert
Organization Name: Johns Hopkins University
Project Start Date: April 1, 2007
Project End Date: Aug. 31, 2015
FY Total Cost: $405,000


Project Title: Aberrantly Secreted Glycoproteins as Markers of Liver Cancer
Contact Principal Investigator: Anand Mehta
Organization Name: Drexel University
Project Start Date: Aug. 8, 2012
Project End Date: June 30, 2017
FY Total Cost: $311,766


Project Title: Novel Biomarker Validation and Dosing Algorithms for Anemia Management in ESRD
Contact Principal Investigator: Michael Merchant
Organization Name: University of Louisville
Project Start Date: Sept. 20, 2011
Project End Date: Aug. 31, 2016
FY Total Cost: $457,421


Project Title: Role of RAB25 and its Effectors in Breast Cancer Bioengenerics
Contact Principal Investigator: Gordon Mills
Organization Name: University Of Texas MD Anderson Cancer Center
Project Start Date: NA
Project End Date: NA
FY Total Cost: $165,318


Project Title: Proteomic Core
Contact Principal Investigator: Robert Moritz
Organization Name: Institute for Systems Biology
Project Start Date: NA
Project End Date: NA
FY Total Cost: $425,478


Project Title: Analytical Core B
Contact Principal Investigator: Andrew Morris
Organization Name: University of Kentucky
Project Start Date: NA
Project End Date: NA
FY Total Cost: $112,528


Project Title: Discovery, Validation and Clinical Application of Novel, Non-Invasive Biomarkers
Contact Principal Investigator: Marsha Moses
Organization Name: Children's Hospital Corporation
Project Start Date: Sept. 10, 2014
Project End Date: June 30, 2019
FY Total Cost: $233,332


Project Title: Novel APCI Source
Contact Principal Investigator: Eugene Moskovets
Organization Name: Masstech
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2015
FY Total Cost: $164,916


Project Title: Integrating Top-Down and Bottom-Up Models in Systems Biology With Application To
Contact Principal Investigator: T. M. Murali
Organization Name: Virginia Polytechnic Institute and State University
Project Start Date: May 1, 2011
Project End Date: April 30, 2016
FY Total Cost: $425,990


Project Title: Technology Mass Spectrometry
Contact Principal Investigator: Sreekumaran Nair
Organization Name: Mayo Clinic Rochester
Project Start Date: NA
Project End Date: NA
FY Total Cost: $590,434


Project Title: Advanced Proteome Informatics of Cancer
Contact Principal Investigator: Alexey Nesvizhskii
Organization Name: University of Michigan
Project Start Date: May 1, 2010
Project End Date: April 30, 2015
FY Total Cost: $269,827


Project Title: Global Genomic and Proteomic Profiling of African Children with Typhoid Fever
Contact Principal Investigator: Stephen Obaro,
Organization Name: University of Nebraska Medical Center
Project Start Date: Aug. 17, 2012
Project End Date: July 31, 2016
FY Total Cost: $403,364


Project Title: Characterizing Muscle Regulatory Elements with Mass Spectrometry-Based Proteomics
Contact Principal Investigator: Shao-En Ong
Organization Name: University of Washington
Project Start Date: Sept. 23, 2013
Project End Date: Aug. 31, 2018
FY Total Cost: $328,313


Project Title: MD Anderson Cancer Center Spore in Multiple Myeloma
Contact Principal Investigator: Robert Orlowski
Organization Name: University Of Texas MD Anderson Cancer Center
Project Start Date: Sept. 22, 2010
Project End Date: Aug. 31, 2015
FY Total Cost: $2,161,999


Project Title: High Density Peptide Arrays for Cancer-Related Post-Translational Modifications
Contact Principal Investigator: Mary Ozers
Organization Name: Proteovista
Project Start Date: Sept. 20, 2013
Project End Date: Feb. 29, 2016
FY Total Cost: $207,796


Project Title: Aptamer-Based Detection of Cardiac Biomarker Glycosylation States Using Apt-Snap
Contact Principal Investigator: Mary Ozers
Organization Name: Proteovista
Project Start Date: Sept. 1, 2014
Project End Date: July 31, 2016
FY Total Cost: $317,350