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Funding Update: Aug 26, 2011 (rev. 1)

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NIH Grants in Proteomics, July 15 to Aug. 24, Part 1 of 2 (Part 2 is available here.)

Project Title: Purchase of a Thermo Fisher Scientific LTQ Orbitrap XL Mass Spectrometer
Contact Principal Investigator: Jonathan Amster
Organization Name: University of Georgia
Budget Start Date: Aug. 7, 2011
Budget End Date: Aug. 6, 2012
FY Total Cost: $832,030


Project Title: A Universal Electromagnetostatic Tandem-Mass-Spectrometric Dissociation-Cell
Contact Principal Investigator: Douglas Barofsky
Organization Name: Oregon State University
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $352,308


Project Title: Multidimensional Proteomics Platform
Contact Principal Investigator: Mikhail Belov
Organization Name: Battelle Pacific Northwest Laboratories
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $198,393


Project Title: Novel ESI-MS Interface with Increased Sensitivity
Contact Principal Investigator: Vadym Berkout
Organization Name: Masstech
Budget Start Date: Jan. 1, 2011
Budget End Date: March 28, 2012
FY Total Cost: $123,413


Project Title: Biomarkers and Signaling in Tuberculosis
Contact Principal Investigator: William Bishai
Organization Name: Johns Hopkins University
Budget Start Date: Aug. 17, 2011
Budget End Date: July 31, 2012
FY Total Cost: $637,548


Project Title: Networks, Pathways and Dynamics of Lysine Modification
Contact Principal Investigator: Jef Boeke
Organization Name: Johns Hopkins University
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $3,466,010


Project Title: Anesthetic-Induced Cardiac Preconditioning
Contact Principal Investigator: Zeljko Bosnjak
Organization Name: Medical College of Wisconsin
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $1,762,868


Project Title: Protein Secretion Pathways of Mycobacterium Tuberculosis
Contact Principal Investigator: Miriam Braunstein
Organization Name: University of North Carolina Chapel Hill
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $324,501


Project Title: Estrogen-Induced Neuroprotective Mitochondrial Mechanism
Contact Principal Investigator: Roberta Brinton
Organization Name: University of Southern California
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $316,023


Project Title: Discovering a Hidden Proteome in the Human Genome
Contact Principal Investigator: John Chaput
Organization Name: Arizona State University-Tempe
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $289,405


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Project Title: Estrogen and Endothelial Protein Nitrosylation
Contact Principal Investigator: Dongbao Chen
Organization Name: University of California Irvine
Budget Start Date: May 1, 2011
Budget End Date: April 30, 2012
FY Total Cost: $191,250


Project Title: Cell-Free Expression of Human Integral Membrane Proteins for Structural Studies
Contact Principal Investigator: Senyon Choe
Organization Name: Salk Institute for Biological Studies
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $297,001


Project Title: An Integrated Systems Biology Approach for Ovarian Cancer Biomarker Discovery
Contact Principal Investigator: Eleftherios Diamandis
Organization Name: Mt Sinai Hospital-Samuel Lunenfeld Research Institute
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $264,033


Project Title: Proteome-Wide Cellular Immunity Approach to P. Falciparum Antigen Identification
Contact Principal Investigator: Denise Doolan
Organization Name: Queensland Institute of Medical Research
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $597,871


Project Title: Diagonal Capillary Electrophoresis for Phosphorylation and Sialylation Analysis
Contact Principal Investigator: Norman Dovichi
Organization Name: University of Notre Dame
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $285,000


Project Title: Cancer Proteomic Center at Washington University
Contact Principal Investigator: Matthew Ellis
Organization Name: Washington University
Budget Start Date: Aug. 22, 2011
Budget End Date: July 31, 2012
FY Total Cost: $2,199,474


Project Title: Protein Microarray
Contact Principal Investigator: Philip Felgner
Organization Name: University of California Irvine
Budget Start Date: May 1, 2011
Budget End Date: April 30, 2012
FY Total Cost: $143,010


Project Title: Multiplex Serodiagnostic Protein Microarray
Contact Principal Investigator: Philip Felgner
Organization Name: University of California Irvine
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $740,101


Project Title: Analysis of Protein-Ligand Binding on the Proteomic Scale
Contact Principal Investigator: Michael Fitzgerald
Organization Name: Duke University
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $321,081


Project Title: Novel Antigen Identification for an Enterotoxigenic E. Coli Vaccine
Contact Principal Investigator: James Fleckenstein
Organization Name: University of Tennessee Health Science Center
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $374,811


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Project Title: Top Down Proteomics of Myofilaments in Heart Failure
Contact Principal Investigator: Ying Ge
Organization Name: University of Wisconsin Madison
Budget Start Date: Aug. 5, 2011
Budget End Date: April 30, 2012
FY Total Cost: $367,773


Project Title: Mass Spectrometry and Biological Structure
Contact Principal Investigator: David Goodlett
Organization Name: University of Washington
Budget Start Date: March 1, 2011
Budget End Date: Feb. 29, 2012
FY Total Cost: $280,273


Project Title: Glycan Markers for the Early Detection of Breast Cancer
Contact Principal Investigator: William Hancock
Organization Name: Northeastern University
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $293,780


Project Title: Effects of Alzheimer's Disease on Hippocampal Alpha7-Nachr Protein Interactors
Contact Principal Investigator: Edward Hawrot
Organization Name: Brown University
Budget Start Date: Aug. 1, 2011
Budget End Date: May 31, 2012
FY Total Cost: $159,086


Project Title: Identification of Biomarkers for Early Detection of Renal Cell Carcinoma
Contact Principal Investigator: Othon Iliopoulos
Organization Name: Massachusetts General Hospital
Budget Start Date: Aug. 5, 2011
Budget End Date: July 31, 2012
FY Total Cost: $465,383


Project Title: Identification of Prostate Cancer Stage in Hispanics Using Serum Protein Profile
Contact Principal Investigator: Margarita Irizarry-Ramirez
Organization Name: University of Puerto Rico Medical Sciences
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $111,375


Project Title: Molecular Genetics Of BBS
Contact Principal Investigator: Nicholas Katsanis
Organization Name: Duke University
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $408,226


Project Title: Mass Spectrometric Studies of Thiotemplate Biosynthesis
Contact Principal Investigator: Neil Kelleher
Organization Name: Northwestern University
Budget Start Date: July 1, 2011
Budget End Date: June 30, 2012
FY Total Cost: $292,228


Project Title: Time Resolved Assay of Synaptic Enzyme Activity by Mass Spectrometry
Contact Principal Investigator: Mary Kennedy
Organization Name: California Institute of Technology
Budget Start Date: July 19, 2011
Budget End Date: April 30, 2012
FY Total Cost: $479,406


Project Title: Disease Determinants of Urban Leptospirosis
Contact Principal Investigator: Albert Ko
Organization Name: Yale University
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $643,735


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Project Title: High-Throughput System for Protease Activity Profiling
Contact Principal Investigator: Igor Kozlov
Organization Name: Prognosys Biosciences
Budget Start Date: Aug. 16, 2011
Budget End Date: July 31, 2012
FY Total Cost: $1,119,536


Project Title: Generation and Proteome-Wide Screening of Hybrid Combinatorial Libraries
Contact Principal Investigator: Jun Liu
Organization Name: Johns Hopkins University
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $811,800


Project Title: Impact of Non-Canonical Decoding on the Proteome
Contact Principal Investigator: Joseph Loo
Organization Name: University of California Los Angeles
Budget Start Date: Aug. 1, 2011
Budget End Date: July 31, 2012
FY Total Cost: $301,871


Project Title: Antibody Biomarkers for Early Detection of Tuberculosis
Contact Principal Investigator: Mitchell Magee
Organization Name: Arizona State University-Tempe
Budget Start Date: Aug. 15, 2011
Budget End Date: July 31, 2012
FY Total Cost: $639,989

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