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Funding Update: Jun 3, 2011

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NIH Grants in Proteomics, April 29 to June 2

Project Title: Widely Distributed Software for Using Mass Spectrometry to Identify Glycans
Contact Principal Investigator: Wayne Bern
Organization Name: Palo Alto Research Center
Project Start Date: July 19, 2010
Project End Date: April 30, 2014
FY Total Cost: $372,601


Project Title: Gene Prediction by Markov Models and Complementary Methods
Contact Principal Investigator: Mark Borodovsky
Organization Name: Georgia Institute of Technology
Project Start Date: March 15, 1993
Project End Date: March 31, 2013
FY Total Cost: $577,264


Project Title: Novel Materials and Methods for Separations of Glycopeptides and Glycans
Contact Principal Investigator: Barry Boyes
Organization Name: Advanced Materials Technology
Project Start Date: May 1, 2011
Project End Date: April 30, 2012
FY Total Cost: $199,641


Project Title: Identification of Proteins Important for Male Osteoporosis
Contact Principal Investigator: Hong-Wen Deng,
Organization Name: Tulane University of Louisiana
Project Start Date: Sept. 18, 2009
Project End Date: July 31, 2014
FY Total Cost: $1


Project Title: Mass Spectrometry-Based Molecular Imaging of Native Biological Nanodomains
Contact Principal Investigator: Francisco Fernandez-Lima
Organization Name: Texas A&M University System
Project Start Date: Aug.1, 2010
Project End Date: April 30, 2012
FY Total Cost: $74,181


Project Title: Biomarkers for Niemann-Pick C Disease
Contact Principal Investigator: Yiannis Ioannou
Organization Name: Mount Sinai School of Medicine
Project Start Date: May 1, 2010
Project End Date: April 30, 2014
FY Total Cost: $351,972


Project Title: Understanding the Mechanism and Role of Cell Membrane Repair in Miyoshi Myopathy
Contact Principal Investigator: Jyoti Jaiswal
Organization Name: Children's Research Institute
Project Start Date: July 2, 2008
Project End Date: April 30, 2013
FY Total Cost: $323,668


Project Title: Acquisition of a High-Field Dual Source FTICR-MS for Pharmaceutical Research
Contact Principal Investigator: Lingjun Li
Organization Name: University of Wisconsin Madison
Project Start Date: May 15, 2011
Project End Date: April 30, 2012
FY Total Cost: $2,070,000


Project Title: FAIMS-Selected Reaction Monitoring to Quantitative Protein Networks in Disease
Contact Principal Investigator: Robert Moritz
Organization Name: Institute for Systems Biology
Project Start Date: May 15, 2011
Project End Date: May 14, 2012
FY Total Cost: $576,434


Project Title: Dry Eye in Postmenopause
Contact Principal Investigator: Kelly Nichols
Organization Name: Ohio State University
Project Start Date: April 1, 2007
Project End Date: March 31, 2012
FY Total Cost: $320,760


Project Title: Histone Modifications by Ethanol: Mechanism & Consequence
Contact Principal Investigator: Shivendra Shukla
Organization Name: University of Missouri-Columbia
Project Start Date: May 15, 2007
Project End Date: April 30, 2012
FY Total Cost: $316,697

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.