Recent NSF Awards in Proteomics and Protein Research
Title: Integrative Bioinformatics for Knowledge Discovery of PTM Networks
Principle Investigator: Cathy Wu, Vijay Shanker, Jung-Youn Lee
Sponsor: University of Delaware
Start/End Date: July 1, 2011 – June 30, 2012
Amount Awarded to Date: $380,678
Funds the development of a bioinformatics research infrastructure for integrated understanding of plant post-translational modifications in a systems biology context. The work will integrate text mining, data mining, data analysis and visualization tools, and databases and ontologies into a research resource to explore and discover PTM networks.
Title: Diffusing Probes of kT-scale Specific Protein-Protein and Protein-Carbohydrate Interactions
Principle Investigator: Michael Bevan
Sponsor: Johns Hopkins University
Start/End Date: June 1, 2011 – May 31, 2012
Amount Awarded to Date: $106,334
Funds work using diffusing colloidal probe microscopy to measure the interactions of surface immobilized proteins and carbohydrates with the ultimate aim of developing capabilities for measuring weak interactions between proteins and carbohydrates on synthetic materials to enable various biomedical applications.