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Funding Update: Apr 15, 2011

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Recent NSF Awards in Proteomics and Protein Research

Title: Waterborne Chemical Cues in the Plankton: A Systems Biology Approach
Principal Investigator: Julia Kubanek, Facundo Fernandez
Sponsor: Georgia Institute of Technology
Start/End Date: Oct. 1, 2011 – Sep. 30, 2014
Amount Awarded to Date: $545,870

Funds a project to investigate the release of chemicals by phytoplankton as a means of inhibiting environmental competitors. The project will use mass spec-based proteomics to investigate the protein expression of the red tide dinoflagellate Karenia brevis to see what proteins are up- or down-regulated in response to challenges by competitors.


Title: Photonic Devices Based on Fluorescent Proteins
Principal Investigator: Seok Yun
Sponsor: Massachusetts General Hospital
Start/End Date: July 1, 2011 – June 30, 2014
Amount Awarded to Date: $360,000

Funds an effort to investigate the optical amplification characteristics of fluorescent proteins with the ultimate aim of developing protein-based lasers that could be used in imaging and analyte sensing for bioengineering and medical diagnosis.


Title: Impedance-Based Bioelectronic Tongue that Incorporates Antibodies
Principal Investigator: Ian Suni, Stephanie Schuckers
Sponsor: Clarkson University
Start/End Date: June 1, 2011 – May 31, 2014
Amount Awarded to Date: $345,485

Funds work on developing a bioelectronic tongue for the detecting of proteins using an array of antibody-coated electrodes interrogated by impedance methods. The researchers will demonstrate the simultaneous detection of three allergenic proteins from a protein mixture using the device.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.