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Funding Update: Mar 25, 2011

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NIH Grants in Proteomics, Oct. 22 to March 23, Part 1 of 2

Title: Role Of O-Glcnac in Human Embryonic Stem Cell Pluripotency and Differentiation
Contact Principal Investigator: Lissette Andres
Organization: University of California Berkeley
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $39,922


Title: Investigations of Bacterial Biofilm Proteomes Using Artifical Amino Acids
Contact Principal Investigator: Nicholas Ball
Organization: California Institute of Technology
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $45,590


Title: The Lysosome of Trypanosoma Brucei: A Proteomic Analysis
Contact Principal Investigator: James Bangs
Organization: University of Wisconsin Madison
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $197750


Title: Markers for HCV-Related HCC: Plasma Profiling, Targeted Strategies and Validation
Contact Principal Investigator: Laura Beretta,
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: March 1, 2011
Project End Date: Feb. 29, 2012
FY Total Cost by IC: $328,680


Title: Providing Peptide Atlas Based Services Through the caGRID Infrastructure
Contact Principal Investigator: John Boyle
Organization: Institute for Systems Biology
Project Start Date: Jan. 1, 2011
Project End Date: June 30, 2011
FY Total Cost by IC: $134,908


Title: Imaging Mass Spectrometry Research Resource at Vanderbilt University
Contact Principal Investigator: Richard Caprioli
Organization: Vanderbilt University
Project Start Date: Feb. 15, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $2,191,734


Title: Impact of Pregnancy on Drug Absorption, Disposition and End Organ Response
Contact Principal Investigator: Steve Caritis
Organization: Magee-Women's Research Institute and Foundation
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $909,885


Title: Longitudinal SIT Trial Plasma Proteomic Biomarker Discovery and Validation in SCI
Contact Principal Investigator: James Casella
Organization: Johns Hopkins University
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $397,909


Title: Surface Analysis Facility for Biomedical Problems
Contact Principal Investigator: David Castner
Organization: University of Washington
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $956,958


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Title: Epigenetic Gene Regulation by the Ocular Environment
Contact Principal Investigator: Peter Chen
Organization: University of Texas Southwestern Medical Center/Dallas
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $279,774


Title: Immune Response of Mosquitoes to Filarial Worms
Contact Principal Investigator: Bruce Christensen
Organization: University of Wisconsin Madison
Project Start Date: March 1, 2011
Project End Date: Feb. 29, 2012
FY Total Cost by IC: $338,919


Title: Sequential Ion/Ion Reactions for Large Peptide and Whole Protein Characterization
Contact Principal Investigator: Joshua Coon
Organization: University of Wisconsin Madison
Project Start Date: March 1, 2011
Project End Date: Feb. 29, 2012
FY Total Cost by IC: $230,989


Title: Cancer Center Support Grant
Contact Principal Investigator: Lawrence Corey
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $2,744,482


Title: Chemical Approaches for Activity-Based Proteomics
Contact Principal Investigator: Benjamin Cravatt
Organization: Scripps Research Institute
Project Start Date: March 1, 2011
Project End Date: Feb. 29, 2012
FY Total Cost by IC: $306,283


Title: Ethanol Hepatotoxicity and NO-Dependent Mitochondrial Dysfunction
Contact Principal Investigator: Victor Darley-Usmar
Organization: University of Alabama at Birmingham
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $262,523


Title: The Role of the PI3K-AKT Pathway in Melanoma Brain Metastasis
Contact Principal Investigator: Michael Davies
Organization: University of Texas MD Anderson Cancer Center
Project Start Date: Feb. 9, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $327,850


Title: The Cell Biology of Coronavirus Infection
Contact Principal Investigator: Mark Denison
Organization: Vanderbilt University
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $314,719


Title: The Role of Histone Phosphorylation in Arsenic-Induced Cell Transformation
Contact Principal Investigator: Zigang Dong
Organization: University of Minnesota Twin Cities
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $302,717


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Title: Protein Biomarkers for Invasive Aspergillosis Diagnostics
Contact Principal Investigator: Marta Feldmesser
Organization: Albert Einstein College of Medicine
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $213,888


Title: Identification of Transamidated Proteins Involved in Cell Death Induction
Contact Principal Investigator: Bassam Fraij
Organization: Benedict College
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $95,324


Title: Oxidative Response Networks in Chagasic Cardiomyopathy
Contact Principal Investigator: Nisha Garg
Organization: University of Texas Medical Branch at Galveston
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $366,750


Title: SYK and Associated Proteins in Breast Cancer
Contact Principal Investigator: Robert Geahlen
Organization: Purdue University West Lafayette
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $226,236


Title: BindingDB: A Tool for Drug Discovery, Modeling and Chemical and Molecular Biology
Contact Principal Investigator: Michael Gilson
Organization: University of California San Diego
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $468,007


Title: Proteomic Assays of Neuronal Protein Palmitoylation
Contact Principal Investigator: William Green
Organization: University of Chicago
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $213,089


Title: Mitochondrial Dysfunction and Chemoresistance in Malignant Gliomas
Contact Principal Investigator: Corinne Griguer
Organization: University of Alabama at Birmingham
Project Start Date: Jan. 1, 2011
Project End Date: Dec.31, 2011
FY Total Cost by IC: $143,387


Title: HIV1 NEF and Viral Infectivity
Contact Principal Investigator: John Guatelli
Organization: Veterans Medical Research Foundation
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $344,239


Title: Cataloging the Subcellular and Suborganellar Proteomes of Sequenced Genomes
Contact Principal Investigator: Chittibabu Guda
Organization: University of Nebraska Medical Center
Project Start Date: Sept. 3, 2010
Project End Date: Aug. 31, 2011
FY Total Cost by IC: $147,015


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Title: Mass Spectrometry-Based Approaches to Study Protein Ubiquitination
Contact Principal Investigator: Steven Gygi
Organization: Harvard University Medical School
Project Start Date: Feb. 1, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $485,067


Title: Continuous-Flow, Ampholyte-Free PI-Based Sorting Peptides/Proteins at Extreme pH
Contact Principal Investigator: Jongyoon Han
Organization: Massachusetts Institute of Technology
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $173,550


Title: Ubiquitin-Mediated Proteolysis and Cell Cycle Control
Contact Principal Investigator: Jeffrey Harper
Organization: Harvard University Medical School
Project Start Date: Feb. 15, 2011
Project End Date: Jan. 31, 2012
FY Total Cost by IC: $398,785


Title: Exploiting TOR Signaling for Cancer Drug Discovery
Contact Principal Investigator: Jing Huang
Organization: University of California Los Angeles
Project Start Date: March 1, 2011
Project End Date: Feb. 29, 2012
FY Total Cost by IC: $263,340


Title: Comprehensive Profiling of Ubiquitination In Neurons
Contact Principal Investigator: Samie Jaffrey
Organization: Weill Medical College of Cornell University
Project Start Date: Dec. 1, 2010
Project End Date: Nov. 30, 2011
FY Total Cost by IC: $190,125


Title: Enabling Studies of Proteome Dynamics
Contact Principal Investigator: Takhar Kasumov
Organization: Case Western Reserve University
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $174,859


Title: Human Proteome Arrays for Auto-Antibody Identification in Clinical Cancer Studies
Contact Principal Investigator: John Kenten
Organization: Meso Scale Diagnostics
Project Start Date: March 1, 2011
Project End Date: Feb. 28, 2012
FY Total Cost by IC: $345,315


Title: New Technology for Functional Studies of the Kinome
Contact Principal Investigator: Igor Kozlov
Organization: Prognosys Biosciences
Project Start Date: Jan. 1, 2011
Project End Date: Dec. 31, 2011
FY Total Cost by IC: $263,924

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.