Recent NSF Awards in Proteomics and Protein Research
Title: Acquisition of a MALDI-ToF Mass Spectrometer for Research and Education
Principal Investigator: Bruce Bowler, Charles Thompson, Michele McGuirl, Klara Briknarova, Stephen Sprang
Sponsor: University of Montana
Start/End Date: Oct. 1, 2010 – Sept. 30, 2013
Amount Awarded to Date: $238,580
Funds the purchase of a MALDI-ToF mass spectrometer for research training and education with a particular focus on proteomics research into synaptic vesicles, cellular targets of organophosphate insecticides, the replication/transcription complex of arenaviruses, and lapidated virulence factors.
Title: Acquisition of a Proteomics Analyzer to Elucidate Pathways of Petroleum Hydrocarbon Bioremediation in the Gulf of Mexico
Principal Investigator: Kartik Chandran
Sponsor: Columbia University
Start/End Date: Sept. 15, 2010 – Aug. 31, 2011
Amount Awarded to Date: $200,000
Funds a study of the microbial mechanisms of methane and complex petroleum hydrocarbon biodegradation at the quantitative proteomics level with the intention of obtaining information that can be used to develop bioremediation strategies to alleviate the environmental damage resulting from the Deepwater Horizon oil spill in the Gulf of Mexico.
Title: Community-Driven Proteomics Analysis Environment
Principal Investigator: Eugene Kolker
Sponsor: Children's Hospital and Regional Medical Center
Start/End Date: Sept. 1, 2010 – Aug. 31, 2011
Amount Awarded to Date: $636,254
Funds the development of SPIRE (Systematic Protein Investigative Research Environment) – a community-driven high-throughput proteomics analysis environment aimed at reducing the tool development and management burden on individual researchers. SPIRE will be a modular system encompassing each stage of mass spectrometry proteomics analysis, from experimental design to peptide identification and protein expression analysis.