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Funding Update: Jun 25, 2010 (rev. 1)

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NIH Grants in Proteomics, May 8 to June 25, Part 1 of 2

Title: LTQ Orbitrap Velos Mass Spectrometer System
Principal Investigator: Ruth Hogue Angeletti
Organization: Albert Einstein College of Medicine Yeshiva University
Start Date: June 10, 2010
End Date: June 9, 2011
Amount in FY 2010: $963,205


Title: Linear Quadrupole/Linear Ion Trap LC/MS/MS Mass Spectrometer
Principal Investigator: Rodney C. Baker
Organization: University of Mississippi Medical Center
Start Date: April 22, 2010
End Date: April 21, 2011
Amount in FY 2010: $441,632


Title: Proteomic Analyses of Pediatric Systemic Lupus Erythematosus
Principal Investigator: Imelda Marie Balboni
Organization: Stanford University
Start Date: July 10, 2009
End Date: May 31, 2014
Amount in FY 2010: $130,761


Title: Alphabeta and Proteomic Analysis of CSF in AD and Aging
Principal Investigator: Randall J Bateman
Organization: Washington University
Start Date: Sept. 1, 2007
End Date: May 31, 2011
Amount in FY 2010: $188,680


Title: Proteomic Characterization of the Sigma-1 Receptor and Its Signaling Complex
Principal Investigator: Carthene R Bazemore-Walker
Organization: Brown University
Start Date: June 1, 2009
End Date: May 31, 2011
Amount in FY 2010: $202,396


Title: Exposure and Biological Response Biomarkers of Cigarette Smoke
Principal Investigator: Ian Alexander Blair
Organization: University of Pennsylvania
Start Date: Aug. 15, 2007
End Date: May 31, 2011
Amount in FY 2010: $579,444


Title: Identification of Novel Arenavirus Protein-Host Cellular Protein Interactions
Principal Investigator: Jason W. Botten
Organization: University of Vermont & State Agricultural College
Start Date: June 15, 2010
End Date: May 31, 2012
Amount in FY 2010: $227,126


Title: Peptide and Protein Biomarkers for Amyotrophic Lateral Sclerosis (ALS)
Principal Investigator: Robert P Bowser
Organization: University of Pittsburgh at Pittsburgh
Start Date: June 1, 2009
End Date: May 31, 2014
Amount in FY 2010: $328,093


Title: Functional Proteomics in Differentiating Erythroid Cells
Principal Investigator: Jorg Bungert
Organization: University of Florida
Start Date: May 15, 2010
End Date: April 30, 2014
Amount in FY 2010: $328,796


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Title: High-Throughput Proteomic Study of Protective Immunity in Human Cholera Infection
Principal Investigator: Richelle C Charles
Organization: Massachusetts General Hospital
Start Date: June 1, 2010
End Date: April 30, 2015
Amount in FY 2010: $136,318


Title: 5500 Qtrap Mass Spectrometer For Yale University, Keck Laboratory
Principal Investigator: Christopher Michael Colangelo
Organization: Yale University
Start Date: May 27, 2010
End Date: May 26, 2011
Amount in FY 2010: $491,747


Title: A Proteomic Interrogation of the Histone Code During HCMV Infection
Principal Investigator: Peter A. Dimaggio
Organization: Princeton University
Start Date: April 1, 2010
End Date: March 31, 2013
Amount in FY 2010: $45,590


Title: Proteomic and Biochemical Studies of BAX Regulatory Proteins in Apoptosis
Principal Investigator: Yuchun Du
Organization: University of Arkansas at Fayetteville
Start Date: May 15, 2010
End Date: April 30, 2011
Amount in FY 2010: $118,054


Title: Peptide and Protein Identification via Tandem MS and Mixed-Integer Optimization
Principal Investigator: Christodoulos Achilleus Floudas
Organization: Princeton University
Start Date: May 1, 2007
End Date: April 30, 2011
Amount in FY 2010: $257,169


Title: Proteomic Strategies for AIDS and Drug Abuse – HIV and Meth CNS Synergy
Principal Investigator: Howard S. Fox
Organization: University of Nebraska Medical Center
Start Date: Sept. 30, 2008
End Date: May 31, 2011
Amount in FY 2010: $945,515


Title: Compartmental Analysis of Proteomic Biomarkers During Intra-Uterine Infections
Principal Investigator: Peta Louise Grigsby
Organization: Oregon Health and Science University
Start Date: June 13, 2008
End Date: May 31, 2012
Amount in FY 2010: $246,510


Title:Proteomics of Porphyromonas Gingivalis Interactions with Fusobacterium nucleatum
Principal Investigator: Murray Hackett
Organization: University of Washington
Start Date: Jan. 1, 2002
End Date: May 31, 2014
Amount in FY 2010: $501,557


Title: A Quantitative Proteomics Approach to Understand Viral Immune Evasion Strategies
Principal Investigator: Michele E Hardy
Organization: Montana State University
Start Date: June 1, 2009
End Date: May 31, 2011
Amount in FY 2010: $177,994


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Title: Integrated Genomewide Analysis of the LPL1 Kinase Signaling Network
Principal Investigator: Tony Hazbun
Organization: Purdue University
Start Date: Aug. 3, 2009
End Date: May 31, 2013
Amount in FY 2010: $248,085


Title: Proteomic Analyses Following Deafness
Principal Investigator: Richard L. Hyson
Organization: Florida State University
Start Date: June 1, 2010
End Date: May 31, 2012
Amount in FY 2010: $168,371


Title: Analysis and Design of Interaction Specifically in Proteins Regulating Apoptosis
Principal Investigator: Amy E Keating
Organization: Massachusetts Institute of Technology
Start Date: Aug. 1, 2008
End Date: May 31, 2012
Amount in FY 2010: $287,687


Title: Quantitative Mass Spectrometry Assays to Detect Multiple Myeloma and Assess Relapse
Principal Investigator: John Matthew Koomen
Organization: H. Lee Moffitt Cancer Center & Research Institute
Start Date: June 1, 2009
End Date: May 31, 2011
Amount in FY 2010: $183,700


Title: Arrays for Protease Activity Profiling
Principal Investigator: Igor A. Kozlov
Organization: Prognosys Biosciences
Start Date: April 15, 2008
End Date: May 31, 2012
Amount in FY 2010: $743,138


Title: Macronutrients, Mitochondria and Blood Metabolome/Proteome Disease Risk Profiles
Principal Investigator: Bruce S Kristal
Organization: Brigham and Women's Hospital
Start Date: Aug. 15, 2007
End Date: May 31, 2011
Amount in FY 2010: $431,098


Title: Genomic and Proteomic Biomarkers of Biological Responses to Exposure
Principal Investigator: Coral Lamartiniere
Organization: University of Alabama at Birmingham
Start Date: Aug. 15, 2007
End Date: May 31, 2011
Amount in FY 2010: $471,237


Title: Identification of Proteins that Structure the Endoplasmic Reticulum
Principal Investigator: Tina H Lee
Organization: Carnegie-Mellon University
Start Date: June 1, 2010
End Date: May 31, 2012
Amount in FY 2010: $133,824


Title: Defining the Isoaspartome
Principal Investigator: Cheng Lin
Organization: Boston University Medical Campus
Start Date: June 1, 2007
End Date: May 31, 2012
Amount in FY 2010: $296,169


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Title: Statistical Methods for Correlated and High-Dimensional Biomedical Data
Principal Investigator: Xihong Lin
Organization: Harvard University
Start Date: Dec. 15, 1997
End Date: March 31, 2011
Amount in FY 2010: $312,162


Title: Proteomic Analysis of Eukaryotic Protein Synthesis
Principal Investigator: Andrew J Link
Organization: Vanderbilt University
Start Date: Feb. 1, 2002
End Date: May 31, 2011
Amount in FY 2010: $334,323


Title: Proteomic Analysis of Eukaryotic Protein Synthesis
Principal Investigator: Andrew J Link
Organization: Vanderbilt University
Start Date: June 14, 2010
End Date: May 31, 2011
Amount in FY 2010: $131,244


Title: Developing a Protein Microarray Technology for High Throughput Proteomic Research
Principal Investigator: Donghui Ma
Organization: Origene Technologies
Start Date: June 1, 2010
End Date: May 31, 2011
Amount in FY 2010: $256,200


Title: Thermo Fisher LTQ-Orbitrap Xl Mass Spectrometer
Principal Investigator: Michael J Maccoss
Organization: University of Washington
Start Date: May 13, 2010
End Date: May 12, 2011
Amount in FY 2010: $499,950


Title: New Molecular Probes for Protein Kinases
Principal Investigator: Dustin J Maly
Organization: University of Washington
Start Date: June 15, 2010
End Date: May 31, 2011
Amount in FY 2010: $99,999


Title: Upgrade of Our Thermo LTQ To a LTQ Orbitrap XL ETD Mass Spectrometer
Principal Investigator: Robert Matthews
Organization: University of Massachusetts Medical School
Start Date: June 18, 2010
End Date: June 17, 2011
Amount in FY 2010: $500,000

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.