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Funding Update: Jan 29, 2010

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Recent NSF Awards in Proteomics and Protein Research

Title: Acquisition of an LC-MS System to Enhance Undergraduate Research That Interfaces Chemistry and Biology
Principal Investigators: Kevin Minbiole; Daniel Downey; Reid Harris; Debra Mohler; Gina MacDonald
Sponsor: James Madison University
Start/End Date: Jan. 15, 2010 – Dec. 31, 2012
Amount Awarded to Date: $299,810

Supports the purchase of an LC-MS platform to, among other things, characterize anti-fungal metabolites from the skin bacteria of frogs and salamanders; study interactions between DNA and chromatin; and measure neurotransmitter metabolites in blood.


Title: Acquisition of a High Resolution Q-TOF Mass Spectrometer
Principal Investigators: Jim Lawrence ; John Droske; Nathan Bowling; Don Guay
Sponsor: University of Wisconsin-Stevens Point
Start/End Date: Jan. 15, 2010 – Dec. 31, 2010
Amount Awarded to Date: $469,942

Funds the purchase of an LC-Q-TOF system. Currently, seven research projects are being conducted at the school that require high-resolution mass spectrometry, according to the abstract. A high-resolution A-TOF system would be used in upper-level chemistry and biochemistry courses.


Title: Acquisition of a MALDI-TOF Mass Spectrometer
Principal Investigators: Paramjit Arora; Michael Ward; James Canary Sponsor: New York University
Start/End Date: Jan. 1, 2010 – Dec. 31, 2012
Amount Awarded to Date: $295,919

Among the projects that the instrument would be used for are ones looking into protein mimetics; bioaffinity interactions and microarray technologies, and "charge transfer interactions in crystals and their relevance to MALDI mass spectrometry," according to the abstract.


Title: Acquisition of a Benchtop Electrospray Ionization Time-of-Flight Mass Spectrometer
Principal Investigators: Vaidhyanathan Ramamurthy; Angel Kaifer; Francisco Raymo; Norito Takenaka; Burjor Captain
Sponsor: University of Miami
Start/End Date: Jan. 1, 2010 – Dec. 31, 2012
Amount Awarded to Date: $308,800

Funds the purchase of an LC-MS system, which will be used to study protein signaling pathways, as well as to study molecular self-assembly, and other things.


Title: Acquisition of a Quadrupole Time-of-Flight Mass Spectrometer
Principal Investigators: Christa Colyer; Rebecca Alexander Sponsor: Wake Forest University
Start/End Date: Jan. 1, 2010 – Dec. 31, 2012
Amount Awarded to Date: $442,102

The instrument will be used to support research into "modeling biological networks in Arabidopsis through integration of genomic, proteomic, and metabolomic data," according to the abstract, as well as "affinity-based capillary electrophoresis … to facilitate bioprobe designs and microbe detection."

The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.