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Funding Update: Jan 15, 2009


Principal Investigator: Bruce Wightman
Sponsor: Muhlenberg College
Start/End Date: Dec. 1, 2008 – Nov. 30, 2010
Amount to Date: $85,910
Title: Integration of Bioinformatics into a Biology Curriculum

The university's departments of biology, chemistry, and mathematics and computer science are integrating bioinformatics into their biology and biochemistry classes. The curricular goals are supported by a new genomics and proteomics core laboratory featuring real-time PCR and 2D gel electrophoresis.

"The over-arching mission is to educate more quantitatively-literate biology students," according to the abstract, and "familiarity with basic bioinformatics and computational approaches is increasingly a necessity for professionals in a range of areas related to the life sciences."

Principal Investigator: John Toscano
Sponsor: Johns Hopkins University
Start/End Date: Feb. 1, 2009 – Jan. 31, 2012
Amount to Date: $260,000
Title: Purchase of a Research Grade MALDI-TOF Mass Spectrometer

The instrument is expected to provide routine and specialized analytical mass spectrometry services to about 23 users at the university from five departments and users from nearby institutions. Uses for the instrument include studies in HNO-induced modifications of proteins involved in cardiac signaling pathways.

Principal Investigator: Christopher Makaroff
Sponsor: Miami University (Ohio)
Start/End Date: Feb. 1, 2009 – Jan. 31, 2012
Amount to Date: $326,625
Title: Acquisition of a MALDI-TOF/TOF MS Spectrometer

The instrument will be used for studies into membrane proteins and peptides, ribosomal proteins and proteins involved in zinc transport, and protein interactions, among other things.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.