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European Bioinformatics Institute, Bio-Rad

The European Bioinformatics Institute has released an updated version of the International Protein Index database at The database, compiled from UniProt, RefSeq, Ensembl, TAIR, and H-InvDB, includes protein data for human, mouse, rat, zebrafish, Arabidopsis, chicken, and cow.

Bio-Rad has released the MicroRotofor cell, an instrument for enriching low-abundance proteins for biomarker discovery. According to the company, the MicroRotofor cell enables formerly undetectable proteins to be enriched to levels that allow analysis by 2D gel electrophoresis/mass spectrometry and liquid chromatography/tandem mass spectrometry.
The MicroRotofor cell, a preparative isoelectric focusing device that fractionates complex protein samples in free solution, can be used alone or as a part of a broader separation or purification workflow, Bio-Rad said. The system fractionates by liquid-phase isoelectric focusing, “which is particularly beneficial for proteins that are insoluble or otherwise do not separate well in other, gel-based IEF media,” the company said in a statement.

Clarification: In an interview in the 06-22-06 issue of ProteoMonitor, Michael Schubert’s comments regarding Bruker Daltonics’ manufacturing relationship with Agilent Technologies omitted some details of the companies’ partnership. Agilent develops the ion sources, ion transfer optics, vacuum systems, chassis, and associated control electronics used in the ion trap systems discussed in the interview. Bruker performs the final assembly and testing for the traps, which are built with components developed by Agilent, Bruker, and other third-party providers.
The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.