A team led by researchers at the Swiss Federal Institute of Technology Zurich and the Institute for Systems Biology has developed selected-reaction monitoring mass spec assays for more than 1,000 cancer related proteins in plasma and urine.

The researchers also demonstrated the potential of SRM-MS to efficiently verify candidate protein biomarkers, using the technique to evaluate the usefulness of 30 target proteins added to the existing five-protein panel of Vermillion's OVA1 ovarian cancer diagnostic.

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Differences in DNA methylation could be used to distinguish between DNA samples obtained from identical twins, researchers say.

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