The side effects of a drug can often be traced to its interactions with proteins other than its intended target. Michael Fitzgerald, an associate professor at Duke University, and his colleagues developed a method for getting a proteome-wide look at what proteins a drug interacts with. By coupling a ligand-binding assay to mass spectrometry, their proof-of-principle study, published online in PNAS in May, was able to show to which proteins the immunosuppressant drug cyclosporin A binds.

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.