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Donald Hunt, Mathias Uhlen, Catherine Fenselau

Three individuals were recognized by the Human Proteome Organization during its World Congress this week for their contributions to proteomics research. Donald Hunt, a professor in chemistry and pathology at the University of Virginia, received HUPO’s Distinguished Achievement Award in Proteomics for his work in developing new instrumentation and methods for characterizing proteins and small molecules by mass spectrometry. Hunt was the first person to develop and apply tandem mass spectrometry for protein sequencing.
Mathias Uhlen, a professor of microbiology at the Royal Institute of Technology in Stockholm, Sweden, also was awarded the Distinguished Achievement Award in Proteomics. Among other things, Uhlen cloned and characterized the staphylococcal protein A. His group also described a new principle for affinity reagents called affibodies and showed their use as a research tool and more recently as potential cancer therapeutics.
Finally, Catherine Fenselau, professor of chemistry and biochemistry at the University of Maryland, was given the Distinguished Service Award for her research during the past 25 years on mass spectrometry and its application to pharmacology and biochemistry. Fensleau is a past president of the American Society of Mass Spectrometry.

The Scan

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Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.