Comparison of Trypsin Brands Suggests Inexpensive Varieties Still Suitable for Proteomics Research | GenomeWeb

As the protease most commonly used to digest proteins into peptides for mass spec analysis, trypsin is a key part of most proteomic workflows, with the performance of the enzyme potentially affecting a variety experimental outcomes including sequence coverage and reproducibility.

A number of vendors sell trypsin, with their offerings ranging significantly in price. For instance, porcine trypsin from Promega – generally considered the gold standard within the field – costs $0.41 per μg. Bovine trypsin from Sigma-Aldrich, meanwhile, runs less than $0.01 per μg.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

In PNAS this week: genes involved in histone deacetylation in Arabidopsis, effects of pathogenic presenilin-1 mutations, and more.

After a study finds DNA from antibiotic-resistant bacteria in Beijing smog, residents there worry, according to the New York Times.

Canada begins its search for a chief government science advisor, Nature News reports.

A company is using facial recognition tools to identify genetic disorders from pictures, Technology Review reports.