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Ciphergen Biosystems, EBI, SIB, PIR, Agilent Technologies, European Bioinformatics Institute

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Ciphergen Biosystems, in collaboration with the American Red Cross, will commercialize Protein Equalizer beads, a technology to detect low-abundance proteins in serum samples. The technology uses a combinatorial bead library to concentrate low-abundance proteins and dilute high-abundance proteins.


The EBI, SIB, and PIR have released UniProt 2.0. The database, updated biweekly, contains 1,487,788 entries and can be accessed online at www.uniprot.org. A description of changes made to Uniprot since release 1.0 can be found at http://expasy.org/sprot/relnotes/.


Agilent Technologies has introduced the Multiple Affinity Removal Column, an immunoaffinity HPLC column to remove high-abundance proteins from mouse blood serum. The column removes albumin, immunoglobulin G and transferrin, the three most common proteins found in mouse serum.


The European Bioinformatics Institute has launched Integr8, a browser that assembles information from 179 completely sequenced genomes and their predicted proteomes, which was previously dispersed. Integr8 is available at www.ebi.ac.uk/integr8.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.