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Chemical Pharmaceutical and Toxicology Institute, GeneData, Argonaut Technologies, Varian

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Giulio Vistoli & Alessandro Pedretti of the Chemical Pharmaceutical and Toxicology Institute at the University of Milan have released VEGA1.4.2, the newest version of a program to convert, manage, and visualize 3D protein structures. This version is compatible with Win32, Linux, Irix, and AmigaOs, and includes several new features: REBOL scripting language; PowerNet plugin for connecting directly to PDB with the help of a TCP/IP protocol and a script management interface; an edit atom dialog box; an updated Gasteiger-Marsili charge attribution; and GAMESS output loader.

GeneData has released version 2.0 of GeneData Impressionist, a software package for analyzing 2D gel- and mass spectrometry-derived data. The new version offers scripting capabilities for automating analysis, and classification algorithms for mode-of-action studies and toxicoproteomics applications. GeneData, based in Basel, Switzerland, developed the software in collaboration with Jan van Oostrum, head of proteomics research at Novartis Pharma.

Argonaut Technologies has released version 3.0 of FlashMaster, a software package for use with FlashMaster II and FlashMaster Solo chromatography systems. The new version offers simplified walk-up flash separations requiring fewer initiation steps, improved data visualization during and following data acquisition, and graphic views of on-screen fraction collection racks. In addition, the program tracks user activities and project advancements automatically, responds to flow rate changes, and recovers from accidental power-down events. More information is available at http://www.argotech.com.

Varian has launched its Focus polar-enhanced solid phase extraction product for extracting developmental pharmaceutical compounds from blood plasma and other biological samples. The new technique removes proteins and other biological molecules prior to LC/MS analysis of the samples, allowing up to four times the recovery of polar and non-polar analytes compared to competing methods, the company said. The Focus SPE product comes in a 96-well-plate format.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.