Skip to main content
Premium Trial:

Request an Annual Quote

Charles River Laboratories International, Beckman Coulter, William Emhiser, Timothy Haines, Murray Wigmore, Arpita Das


New Products

Charles River Laboratories International introduced this week a 10-minute assay for protein quantification called the Endosafe PTS-BCA.

The PTS-BCA utilizes a hand-held reader and disposable cartridge pre-loaded with Pierce BCA reagents to run a quantitative protein determination. The test works by measuring the colorimetric change of samples reacting to the BCA reagent, which is a formulation based on bicinochoninic acid. Amino acids in the proteins trigger a reaction to take place, which causes a purple color to develop. The color change is measured by a spectrophotometer in the PTS instrument.

According to Charles River, a primary advantage of the PTS-BCA over conventional BCA protein assays is that there is no need to prepare daily standard curves. In addition, there is no need to incubate protein samples prior to testing.

Beckman Coulter introduced this week the IOTest Anti-Cyclin A2 monoclonal antibody for the study of cell cycle transitions. The antibody is the newest addition to Beckman's universal cytometry reagent line.

Cyclin A2 is important in the transition of the cell cycle to DNA synthesis and replication phases, according to Beckman. The protein is abruptly destroyed as the cell moves into mitosis. The new IOTest Anti-Cyclin A2 monoclonal antibody could be useful in applications such as basic research on cell cycle control, apoptosis and tumorigenesis, and pharmaceutical discovery efforts to identify inhibitors, blockers and antimitotic drugs.


Movers & Shakers

William Emhiser has been appointed as new chief executive of Whatman, the company said on Monday. He replaces Timothy Haines, who was named chief executive in May. Emhiser will take up his appointment on Nov. 1. He is currently president of North American operations for Proteome Systems. Prior to that, he held a number of senior management positions at Millipore. Emhiser holds a degree in biomedical engineering from Duke University.

Murray Wigmore has joined GE Healthcare Canada as general manager for the clinical systems group. Previously, he was senior vice president at MDS Sciex.

Arpita Das has become senior scientist for the protein bioanalytical department of Midwest BioResearch, the Evanston, Ill.-based company said last week. Previously, she was a senior scientist at Neuronautics. Das holds a PhD in cell and developmental biology from the University of Illinois and an MS in molecular biology from Loyola University of Chicago.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.