The Broad Institute of MIT and Harvard has released GenePattern 2.0, an upgrade of its software tool for analyzing gene expression data. GenePattern enables researchers to perform custom data analyses and to record them for later playback. Version 2.0 includes components for analyzing proteomic data.
Version 17 of the Reactome knowledgebase of biological processes in humans is available at http://www.reactome.org. New modules include signaling cascades mediated by TGF-beta, RIG-I, and Toll-like receptors 3 and 4; the conjugation phase of xenobiotic metabolism; aspects of the metabolism of lipoproteins; cell-cycle regulation by the anaphase-promoting complex; and ATR activation in response to replication stress. Reactome now includes 1,828 curated human reactions and 1,369 annotated human proteins.
Movers & Shakers
Eksigent Technologies has hired David Weber as its new CEO and president. Weber, who also becomes a director, joins the company from Stratagene, where he was vice president of global marketing and business.
The Critical Path Institute has appointed Ellen Feigal as its new director of medical devices and imaging. Feigal is on sabbatical from TGen, where she is vice president of clinical sciences and deputy scientific director.
Feigal has a BS in biology and an MS in molecular biology and biochemistry from the University of California, Irvine, and an MD from UC Davis.