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Broad Institute of MIT and Harvard, Reactome, David Weber, Ellen Feigal


New Products

The Broad Institute of MIT and Harvard has released GenePattern 2.0, an upgrade of its software tool for analyzing gene expression data. GenePattern enables researchers to perform custom data analyses and to record them for later playback. Version 2.0 includes components for analyzing proteomic data.

Version 17 of the Reactome knowledgebase of biological processes in humans is available at New modules include signaling cascades mediated by TGF-beta, RIG-I, and Toll-like receptors 3 and 4; the conjugation phase of xenobiotic metabolism; aspects of the metabolism of lipoproteins; cell-cycle regulation by the anaphase-promoting complex; and ATR activation in response to replication stress. Reactome now includes 1,828 curated human reactions and 1,369 annotated human proteins.


Movers & Shakers

Eksigent Technologies has hired David Weber as its new CEO and president. Weber, who also becomes a director, joins the company from Stratagene, where he was vice president of global marketing and business.

The Critical Path Institute has appointed Ellen Feigal as its new director of medical devices and imaging. Feigal is on sabbatical from TGen, where she is vice president of clinical sciences and deputy scientific director.

Feigal has a BS in biology and an MS in molecular biology and biochemistry from the University of California, Irvine, and an MD from UC Davis.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.