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Broad Institute of MIT and Harvard, Reactome, David Weber, Ellen Feigal


New Products

The Broad Institute of MIT and Harvard has released GenePattern 2.0, an upgrade of its software tool for analyzing gene expression data. GenePattern enables researchers to perform custom data analyses and to record them for later playback. Version 2.0 includes components for analyzing proteomic data.

Version 17 of the Reactome knowledgebase of biological processes in humans is available at New modules include signaling cascades mediated by TGF-beta, RIG-I, and Toll-like receptors 3 and 4; the conjugation phase of xenobiotic metabolism; aspects of the metabolism of lipoproteins; cell-cycle regulation by the anaphase-promoting complex; and ATR activation in response to replication stress. Reactome now includes 1,828 curated human reactions and 1,369 annotated human proteins.


Movers & Shakers

Eksigent Technologies has hired David Weber as its new CEO and president. Weber, who also becomes a director, joins the company from Stratagene, where he was vice president of global marketing and business.

The Critical Path Institute has appointed Ellen Feigal as its new director of medical devices and imaging. Feigal is on sabbatical from TGen, where she is vice president of clinical sciences and deputy scientific director.

Feigal has a BS in biology and an MS in molecular biology and biochemistry from the University of California, Irvine, and an MD from UC Davis.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.