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Beyond Genomics, Matritech and Bruker Daltonics, Genome Canada, Syrrx

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Beyond Genomics Signs Wide-Ranging Collaboration with BU

Building on CEO Steve Ober’s close relationship with Aram Chobanian, dean of the Boston University School of Medicine, Waltham, Mass.-based Beyond Genomics has signed a multi-year agreement to collaborate with BU in applying proteomics and other technologies in the study of diseases such as cardiovascular disease, oncology and central nervous system disorders, the two parties said last week.

The agreement is potentially quite broad-ranging, said Beyond Genomics director of marketing Ted Marple, because it will allow BU scientists access to the company’s systems biology technologies for a number of research projects. “It’s not so simple as just getting access to clinical samples,” he said. “It’s very broad, and umbrella-like in structure.”

Marple declined to disclose the financial and intellectual property conditions of the collaboration, but characterized the partnership as involving mutual decisions as to which disease programs to pursue together. Joseph Loscalzo, chairman of the department of medicine at BU, will play a major role in helping guide the research partnership, he added. Loscalzo’s research at BU centers around the vascular biology of nitric oxide and the vascular pathobiology of atherothrombosis.

Although Beyond Genomics will continue to develop partnerships with other commercial and academic parties, Marple said the arrangement with BU “is the focus for now.”

 

Bruker Daltonics to Supply Mass Specs for Matritech Diagnostic Tests

Diagnostic test developer Matritech has signed up Bruker Daltonics to collaborate on protein diagnostic tests for breast and prostate cancer, the two companies said last week. Bruker will supply the MALDI-TOF mass spectrometry and associated sample handing systems, while Matritech will supply the intellectual property for the joint offering, said Steve Chubb, CEO of Matritech. The systems will test patients’ blood for NMP66, a nuclear matrix protein associated with breast cancer, and NMP48, a nuclear matrix protein associated with prostate cancer. Matritech discovered the protein markers using a 2D gel and mass spectrometry platform, Chubb said. The company chose to work with Bruker primarily because of its past relationship with Bruker as an instrument supplier, Chubb added.

 

Genome Canada Awards BIND $8M

Protein interaction database BIND has received CA $12.5 million ($8.14 million) from Genome Canada, ProteoMonitor learned last week. Christopher Hogue, a project leader for BIND, could not be reached for comment, but in the past BIND representatives have said the money will go toward hiring additional curators and validating the interactions in the database generated from yeast two-hybrid experiments.

 

Syrrx Files Infringement Suit Against Oculus Pharmaceuticals

Syrrx filed a patent infringement suit against Oculus Pharmaceuticals earlier this month, claiming the Birmingham, Ala.-based company has infringed on Syrrx’s patent covering nanovolume technology for crystallizing molecules in volumes of less than one microliter. The suit is the first action taken by Syrrx in defense of US Patent 6,296,673, which the company was awarded in February.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.