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BD Biosciences Clontech, GeneCopoeia


BD Biosciences Clontech released the BD Talon Single Step Columns last week and BD Living Colors HcRed Polyclonal Antibody this week. BD Talon purifies histidine-tagged proteins in one step, and can do so directly from bacterial culture, according to the company. A lysis buffer call xTractor lyses the cells while the BD Talon resin binds the proteins. The entire procedure takes 30 minutes, according to the com-pany. The BD Living Colors HcRed antibody detects the red fluorescent protein HcRed1. The antibody detects all forms of HcRed 1 expressed from the company’s HcRed1 Vectors. It has low cross-reactivity with the company’s other fluorescent reporters, according to the company.

GeneCopoeia released this week two new sets of more than 15,000 OmicsLink human ORF clones in vectors containing T7 and CMV promoters, respectively. This adds to GeneCopoeia’s already large collection of full-length ORF clones. The clones allow for direct expression of proteins in E. coli, mammalian cells, or in vitro cell-free translation systems, as well as easy transfer of ORFs to other vector systems. The proteins produced from the clones contain tags for aiding in downstream analysis and experiments. The clones can also be used in automatic platforms for protein crystallization, drug target validation, drug screening, and reverse transfection, according to GeneCopoeia.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.