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Applied Biosystems, Olympus, Proxeon, Integral Molecular, Alpha Innotech

Applied Biosystems introduced this week the TissueView Software for mass spectrometry imaging.
The software makes data processing more intuitive and delivers easier-to-interpret scientific results, giving researchers “a better way to process, visualize, and interpret information that can help pharmaceutical companies select the drug compounds to develop and help academic researchers learn more about biological functions,” the company said in a statement.

Olympus this week launched the FluoroPoint single molecule fluorescence detection system in the US.
The system, used for molecular interaction analysis, has been available elsewhere in the world but is now available to US screening and research laboratories.
The system, which can be used to study protein interactions, as well as DNA, RNA, and receptor binding, provides absolute quantification and yields results for sample volumes as small as 30 microliters, the company said in a statement.

Proxeon launched ProteinCenter v.1.5 this week. The enhanced version of the proteomics data interpretation software produces a map showing the location of all identified proteins within a cell, making it easier to extract results from ProteinCenter “directly into … reports or publications by including several new export formats that support comparison of data sets,” the company said in a statement.

Integral Molecular this week launched Lipoparticles for cell-free analysis of membrane proteins.
Lipoparticle technology “selectively captures and concentrates target cell surface proteins in membrane-enveloped nanoparticles … [and] because of their size and purity, Lipoparticles can be used to analyze receptors using strategies previously suitable only for soluble proteins,” the company said in a statement. Lipoparticles have been validated for a range of membrane protein targets such as HIV infection and various cancers.

Alpha Innotech this week introduced Red, its newest gel imaging system.
The system’s integrated transillumination and epi illumination, combined with its three-position filter wheel, allows for imaging across a variety of UV fluorescent labels commonly used in protein and DNA gels, such as ethidium bromide, SYBR Green, SYRB Safe, and Hoechst Blue.

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.