Skip to main content
Premium Trial:

Request an Annual Quote

Anderson Forschung to Develop Assay for Biomarker Quantitation for BiOasis

NEW YORK (GenomeWeb News) – BiOasis said today that it has tapped the Anderson Forschung Group to develop a new proteomics assay for diagnosing Alzheimer’s disease.
Under the agreement, Anderson Forschung will develop an assay using a technique called Stable Isotope Standards and Capture by Anti-Peptide Antibodies, a proteomics platform aimed at biomarker quantification and qualification.  
The SISCAPA technique was developed to measure protein levels in human plasma and is based on immunoaffinity enrichment of peptide surrogates of biomarker proteins and their identification by mass spectrometry.
The company said that the technique improves standard immunoassays because the analytes are identified by mass spectrometry, the assay detects peptide surrogates rather than protein targets, allowing for less variability due to degradation, and it is less subject to interference caused by antibodies that bind the analyte because those are destroyed during the sample preparation step.
BiOasis, based in Surrey, BC, will use SISCAPA as a second, independent method for quantification of p97 in human plasma in parallel with a sandwich immunoassay, which could add confidence for qualification of the biomarker for Alzheimer’s disease.
Financial terms of the agreement were not released.
Leigh Anderson, the founder of Anderson Forschung, is a member of BiOasis's scientific advisory board. 

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.