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Agilent Technologies, Millipore, AnaSpec, Tripos

Agilent Technologies last week launched its EZChrom Elite 3.2 software for use with HPLC data. In addition to compatibility with Agilent’s 1200 Series liquid chromatographers, the software works with all makes of LCs, an Agilent spokesman said.
The 3.2 version features a new navigation pane for easy access to software functions and analysis tools that allow users to specify custom identifiers and analysis parameters on a peak-by-peak or injection basis directly in the sequence table, the company said.

Millipore launched this week the first round of adenoviral shRNA expression vector reagents targeting the human druggable genome. The classes included in this release represent all the major protein classes amenable to small-molecule intervention, the company said in a statement. That includes kinases, GPCRs, and secreted proteins.
The AdenoSilence vectors are available in three different sequence variants sold separately or as a kit. The vectors “allow for single-step delivery of shRNA through the direct application of the virus supernatants onto a primary cell culture, thereby making any additional transfection reagents or complex transfection protocols unnecessary,” Millipore said.

AnaSpec released three protein phosphatase assay kits this week. The fluorimetric EnzoLyte FDP assay kit is optimized for assaying protein phosphatases requiring a pH of at least 6.5 for optimal activity, the company said in a statement. Its EnzoLyte MFP assay kit, also a fluorimetric assay, is for phosphatases that require a pH of no more than 6.5. AnaSpec’s colorimetric kit, the EnzoLyte pNPP assay kit, utilizes p-nitrophenyl phosphate as a substrate and shows high sensitivity and a wide linear range. The detection limit is generally 3 ng or lower.

Tripos this week launched the Advanced Protein Modeling software package combining homolog identification, sequence alignment, and interactive comparative protein structure modeling. APM is available as an optional component of Tripos’ SYBYL 7.3 product line and is based on the FUGUE and ORCHESTRAR technologies.

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.