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Agilent Technologies, Kinexus Bioinformatics


Agilent Technologies has introduced new spin cartridges that remove high-abundance proteins from blood serum. The cartridges allow for the depletion of high-abundance proteins using a standard benchtop centrifuge, rather than requiring the more expensive high-performance liquid chromatography instrumentation.

The reusable spin cartridges are based on the same technology as Agilent’s multiple affinity removal LC columns and provide similar performance, the company said.

Kinexus Bioinformatics recently launched its sixth Kinetworks Phospho-Site Screening Service designed to simultaneously detect the presence and relative quantities of 34 protein phosphorylation sites in humans and animal model systems, the Vancouver, Canada-based company announced this week.

Kinexus currently tracks more than 180 protein kinases, 150 phospho-sites in kinase targets and 120 other signaling proteins that regulate cell proliferation, stress responses and apoptosis, according to the company.

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.