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Agilent Technologies, Bio-Rad Laboratories, Fujifilm Life Sciences

At Pittcon this week, Agilent Technologies introduced the 1200 Series High Performance Autosampler SL plus, which the company said “typically” delivers the lowest carryover and highest precision of any autosampler on the market [see related story, this issue].
Carryover is as low as .004 percent and precision is typically less than .5 percent from 2 to 5 microliters and less than .7 percent from 1 to 2 microliters.

Also at Pittcon, a Bio-Rad Laboratories official said the company will be releasing the Proteon Manager Security Edition software and Proteon Installation and Qualification and Operation Qualification kit during the summer.
They are validation and regulatory tools “that will allow us to go to the manufacturing QC environments with the [surface plasmon resonance] device as well as meet the needs of those individuals in clinical research who also begin to assemble their regulator tools so they can cross over into manufacturing software,” said Renee LeMaire Adkins, marketing manager for the protein function division at Bio-Rad.

Fujifilm Life Sciences this week introduced the FLA-9000 modular image scanner for radioisotopic, fluorescent, chemiluminescent, and digitized imaging. Also called Starion, the system is “ideal” for fluorescence detection of 2D gels by SYPRO Ruby stain and digitization of CBB-stained or silver-stained samples, the company said in a statement.
It comes in three models: IP for storage phosphor imaging; RGB Model for multi-spectral 2D gel imaging; and IR+IP Model for conducting near-infrared and radioisotopic imaging. It also offers five different excitation wavelengths, 473 nm, 532 nm, 635nm, 685 nm, and 785 nm, and a dynamic range of up to five orders of magnitude.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.