Proteomics & Protein Research

News on protein analysis, clinical proteomics, biomarkers in genetics, genomics, and molecular diagnostics.

Researchers used a screen of mutation hotspots present in kinase active domains to identify protein kinases commonly inactivated by cancer-linked mutations.

The study used analysis of intact proteins to identify mutation-linked post-translational modifications involved in KRAS activation and membrane attachment.

While mass spec-based single-cell proteomics is still in its infancy, recently developed methods allow the ID of thousands of proteins at the single-cell level.

In a poster at this week's AACR annual meeting, researchers used the firm's tech to investigate how the addition of a cytokine agonist can improve CAR-T treatment.

With a series of recent collaborations in hand, the company is leveraging its experience in autoimmune biomarkers to move into the immunoncology space.

In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.