NEW YORK (GenomeWeb) – Researchers from St. Jude Children's Research Hospital and The Scripps Research Institute today announced the launch of the Human Dark Proteome Initiative (HDPI).

The initiative aims to foster research into the roughly one third of the proteome consisting of proteins that do not adopt defined three-dimensional structures. A number of these so-called intrinsically disordered proteins are implicated in conditions including heart disease, diabetes, and cancer, as well as infectious and neurodegenerative diseases.

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This webinar will demonstrate how a research team at the National Institutes of Health evaluated a novel in situ hybridization approach and applied it to study splice variants related to schizophrenia.