Skip to main content

Sigma-Aldrich to Distribute Olink Products

NEW YORK (GenomeWeb News) – Sigma-Aldrich today said that it has signed an agreement to serve as worldwide distributor of Olink Bioscience's Duolink In Situ products.

The Duolink In Situ products enable researchers to image the locations of single protein-protein interactions, measure protein expression levels, and identify relative changes in post-translational modification events.

The products work in tandem with Sigma Life Science's antibody portfolio to enable researchers to target precise proteins of interest, said Sigma. In addition, the Duolink products can be used in combination with Sigma's CompoZr Zinc Finger Nuclease-mediated gene editing technology to track knocked-out or knocked-in genes, as well as with Sigma's Mission RNA interference technologies for tracking protein expression after gene knockdown.

"The ability to visualize these protein-protein interactions in unmodified cells under endogenous expression and at very low levels is a fundamental advance that allows greater insight into basic biology, pathways, spatial phenomena, and potential therapeutic targets in those pathways," Josef Zihlmann, VP of Sigma Life Science, said in a statement.

Simon Fredriksson, CEO and president of Uppsala, Sweden-based Olink, said that the alliance "will build awareness and develop the market for Duolink In Situ" through Sigma's global sales reach.

Further terms of the agreement were not disclosed.

The Scan

US Supports Patent Waivers

NPR reports that the Biden Administration has announced its support for waiving intellectual property protections for SARS-CoV-2 vaccines.

Vaccines Versus Variants

Two studies find the Pfizer-BioNTech SARS-CoV-2 vaccine to be effective against viral variants, and Moderna reports on booster shots to combat variants.

CRISPR for What Ails You

The Wall Street Journal writes that CRISPR-based therapies could someday be used to treat common conditions like heart attacks.

Nature Papers Review Integration of Single-Cell Assay Data, Present Approach to Detect Rare Variants

In Nature this week: review of ways to integrate data from single-cell assays, and more.