NEW YORK (GenomeWeb) – A team led by researchers at the University of California, San Diego has developed a method for analyzing data-independent acquisition mass spec experiments in an untargeted manner.

Detailed in a paper published this week in Nature Methods, the approach, named MSPLIT-DIA, uses a spectral mapping approach to identify peptides in DIA datasets and, according to its developers, could improve both DIA-based peptide identification and quantification.

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