NEW YORK (GenomeWeb) – Researchers at Northeastern and Harvard Universities have developed a technique that enables mass spectrometry-based proteomics at the single-cell level.

Called Single Cell Proteomics by Mass Spectrometry (SCOPE-MS), the approach uses tandem mass tagging (TMT) to quantify thousands of proteins in single mammalian cells, and is one of the first techniques to bring large-scale mass spec analysis to the single-cell level.

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