NEW YORK – A team led by researchers at the Max Planck Institute of Biochemistry has developed a mass spec workflow for Bruker's timsTOF Pro instrument that combines the parallel accumulation–serial fragmentation (PASEF) method with data-independent acquisition (DIA).
Detailed in a paper published this week in Nature Methods, the method, called diaPASEF, allows for more comprehensive sampling of peptide precursor ions, resulting in more sensitive analyses.
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