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New Products: Feb 25, 2011

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Thermo Fisher Scientific announced this week the release of its new Pierce Protein Molecular Weight Ladders and PageRuler Protein Ladders for monitoring protein separations during gel electrophoresis.

The ladders are available either pre-stained or unstained with the Pierce pre-stained ladder set containing seven single-color proteins varying in size from 14.4 to 116 kilodaltons and the stained set containing six proteins varying from 20 to 120 kilodaltons.

The unstained PageRuler ladder sets come in three molecular weight ranges – a standard set that includes 14 proteins ranging from 10 to 200 kilodaltons; a broad range containing 11 proteins from 5 to 250 kilodaltons; and a low range containing seven proteins from 5 to 100 kilodaltons.

The prestained PageRuler ladders contain 10 proteins ranging from 10 to 170 kilodaltons with two different colored bands for reference. The prestained PageRuler Plus set includes 9 proteins from 10 to 250 kilodaltons with two orange bands and one green band.


Kinexus announced this week that predictions of over 30 million human kinase-substrate interactions are now available at its updated PhosphoNET database.

The database now features information on more than 93,000 experimentally confirmed human phosphorylation sites as well as 560,000 additional phosphorylation sites predicted with a new algorithm, the company said.

The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.