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Movers & Shakers: Jun 10, 2011

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University of Michigan Assistant Professor Brandon Ruotolo received an American Society for Mass Spectrometry 2011 Research Award this week in recognition of his accomplishments with mass spectrometry.

Ruotolo's lab focuses on using mass spec to investigate large protein complexes involved in DNA replication and contributing to protein aggregation diseases like Alzheimer's, type II diabetes, and cancer. Prior to joining the Michigan faculty in 2009, Ruotolo worked as a research fellow under Carol Robinson at the University of Cambridge.

Sponsored by Waters, the award consists of a $35,000 research grant. Awardees are selected by an independent panel of mass spectrometry researchers.


Frank Witney has been named president and CEO of Affymetrix, taking over for Kevin King, who left. Witney also will serve on the company's board of directors.

Witney was previously executive VP and chief commercial officer for Affymetrix, and for the past two years CEO and president of Dionex, which was recently bought by Thermo Fisher Scientific. He was president and CEO of Panomics before the company was acquired by Affymetrix, president and COO at Packard BioScience, and president of drug discovery tools at PerkinElmer Life Sciences after it acquired Packard.


Harvard University professor and cancer institute director Ronald DePinho has been named the next president of the University of Texas MD Anderson Cancer Center in Houston.

DePinho currently is director of the Belfer Institute for Applied Cancer Science at the Dana-Farber Cancer Institute and he is a professor of medicine and genetics at Harvard. He will take over the position in September for John Mendelsohn, who announced he would step down from the presidency last December. Lynda Chin, DePinho's wife and Belfer's current scientific director, also will join the faculty at UT MD Anderson.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.