NEW YORK – Due in large part to its technical complexity, top-down proteomics has remained a relatively small niche within proteomics research.
Recent developments in mass spectrometry could herald an uptick in interest in the technique, however, suggested Neil Kelleher, professor of chemistry at Northwestern University and a leading top-down researcher.
"Is 2019 going to be a tipping point? I can't predict the future," he said. But, he added, new instrument offerings have the potential to expand top-down to a wider audience.