NEW YORK (GenomeWeb) – Researchers at the Institute for Systems Biology have developed a method for improved analysis of protein post-translational modifications using Swath-style data-independent acquisition mass spec.

Detailed in a paper published last month in Molecular & Cellular Proteomics, the approach allows for unbiased detection of protein PTMs with greater sensitivity than is possible using conventional shotgun mass spec, Robert Moritz, an ISB researcher and senior author on the paper, told GenomeWeb.

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