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Case Western Dental School to Use $9.5M from NIH for HIV Studies

NEW YORK (GenomeWeb News) – The Case Western Reserve University School of Dental Medicine has received a grant of $9.5 million from the National Institute for Dental and Craniofacial Research to conduct proteomics and other molecular studies of HIV-infected patients, the university said today.

Among other projects, the five-year grant will fund proteomics studies of how some people are protected against HPV, as well as research into the molecular interactions that impact immunity.

A multidisciplinary group of researchers from dentistry and medicine will discover why HIV-infected people receiving highly active anti-retroviral therapy, or HAART, have increase incidences of contracting HPV.

In a proteomics study, scientists will identify altered proteins in patients taking HAART and will study warts associated with HIV in order to identify genetic changes that could help explain viral resistance in some people.

For more comprehensive coverage of the proteomics studies awarded under this grant, see GenomeWeb Daily News sister publication ProteoMonitor.

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