The Promise

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Part of the promise of personalized medicine is that patients will get treatments tailored to their specific genomic profile and situation. That is, of course, dependent upon physicians knowing to order such tests and being able to interpret the results in light of their patients' particular cases. And it's not clear that they do. A number of studies, including a 2011 Genetics in Medicine study from Baylor College of Medicine researchers, have reported that many physicians do not properly interpret genetic tests and their implications.

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In PNAS this week: co-evolutionary signatures of insect hosts and bacterial symbionts, distinct transcript isoforms of high-grade ovarian cancer, and more.

Adam Rutherford discusses genetic genealogy at the Guardian.

Portions of the US 21st Century Cures Act are raising some safety concerns.

David Dobbs writes at Buzzfeed that genomics has delivered little on its promises.