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A team from the US, South Africa, and Norway takes a look at an extensively drug-resistant Mycobacterium tuberculosis strain called LAM4/KZN that first was first found in HIV patients in South Africa's KwaZulu-Natal province in 2005. The researchers did whole-genome sequencing on more than 300 extensively drug-resistant LAM4/KZN and non-LAM4/KZN clinical isolates collected from 2011 to 2014, which were analyzed phylogenetically alongside geographical clues and other epidemiological insights.

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Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterized by irreversible scarring of the distal lung, leading to respiratory failure.