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Centogene: Mary Sheahan, Berndt Modig

Mary Sheahan has been appointed to the supervisory board of German rare disease company Centogene, pending her confirmation at the company's next general shareholder meeting. As of Dec. 1, she will serve as an interim member of the board. She is also scheduled to become chair of the audit committee. Sheahan is currently CFO of Avillion.

Berndt Modig will step down from Centogene's supervisory board at the next general shareholder meeting. He has been a member of the board since 2018.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.