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Angle: Brett Swansiger, Karen Miller

Liquid biopsy company Angle has appointed Brett Swansiger as chief commercial officer (CCO) and Karen Miller as CSO. Swansiger most recently was CCO at DxTerity Diagnostics. He has also held senior commercial positions at Prometheus Laboratories, Agendia, and MDxHealth. He began his life sciences career at Bristol Myers Squibb.

Miller has more than 30 years of experience in the pharmaceutical industry, and most recently served as CSO at Ixaka. She has also previously held senior executive positions at Vertex Pharmaceuticals, UCB Pharma, GlaxoSmithKline, and Adaptimmune.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.