NEW YORK (GenomeWeb News) – The US Patent and Trademark Office has rejected all 12 claims in a key US patent related to real-time PCR thermal cycler technology that is assigned to Life Technologies' Applied Biosystems subsidiary.

The European Patent Office, meantime, last week issued a decision to maintain the European counterpart of the patent in an "amended form."

The US patent, No. 6,814,934, and titled, "Instrument for monitoring nucleic acid amplification," was granted on Nov. 9, 2004 to inventor Russ Higuchi and assigned to Applied Biosystems.

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