This article has been updated from a previous version to include comments from Bio-Rad.

Quantifying HIV levels in patients on antiviral therapy demands assays able to function well in the lowest ranges. A recent study in PLOS One has shown seminested qPCR to be more reliable for detecting ultra-low levels of cell-associated HIV RNA than droplet digital PCR, in part due to fluorescence in no-template control droplets.

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In PLOS this week: new gene linked to ocular coloboma, new statistical model for interrogating gene expression networks, and more.

With a new collection, PLOS highlights negative results it has published.

A pair of researchers examines political leanings and views on genomics, finding more of a role for optimism and pessimism in people's views.

The genome of the carnivorous bladderwort is smaller than many other plant genomes, but it still holds on to important genes.