Study Finds Digital PCR No Better than Real-Time PCR for Low-Level HIV Detection, Quantification | GenomeWeb

Droplet digital PCR is no better than real-time PCR at detecting and quantifying low levels of cell-associated HIV-1 genetic material from samples taken from patients both on and off antiviral therapy, according to newly published study.

In addition, digital PCR analyses take more time and may be more expensive than real-time PCR for this specific application, said one of the study's authors, who nonetheless also noted that he is "optimistic" about the digital PCR platform — Bio-Rad's QX100 Droplet Digital PCR system — for future similar HIV studies.

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