Skip to main content
Premium Trial:

Request an Annual Quote

Rubicon, Diagenode Partner on ChIP Sample Prep for Next-gen Sequencing

NEW YORK (GenomeWeb News) – Rubicon Genomics will integrate its ThruPlex technology into Diagenode's epigenetics platforms under a partnership announced today.

The deal is expected to result in improved efficiency and quality of DNA sample preparation for chromatin immunoprecipitation applications, Rubicon said.

Under the terms of the deal, Diagenode will incorporate the ThruPlex-FD technology into its MicroPlex Library Preparation Kit for ChIP-seq studies that require small sample amounts.

The ThruPlex-FD NGS Prep kits for synthesizing and amplifying ChIP DNA next-generation sequencing use a one-tube, three-step process for the production of high-quality DNA from small samples, while Diagenodes's products are used to precipitate and recover DNA for ChIP applications from very small amounts of chromatin. The combination of the companies' technologies, Rubicon said, will shorten the amount of time for ChIP sequencing by almost 10 hours and reduce the number of cells needed for ChIP research by no less than 100-fold.

“This partnership with Diagenode extends the reach of our proprietary technology," James Koziarz, CEO of Rubicon, said in a statement. "This partnership is an important example of our collaboration strategy that focuses on combining complementary technologies to offer complete solutions to the research community."

Financial and other terms of the deal were not disclosed.

The Scan

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.

Study Presents New Insights Into How Cancer Cells Overcome Telomere Shortening

Researchers report in Nucleic Acids Research that ATRX-deficient cancer cells have increased activity of the alternative lengthening of telomeres pathway.

Researchers Link Telomere Length With Alzheimer's Disease

Within UK Biobank participants, longer leukocyte telomere length is associated with a reduced risk of dementia, according to a new study in PLOS One.

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.