NEW YORK (GenomeWeb News) – Roche and Caliper Life Sciences today announced a deal aimed at developing an automated target enrichment solution for next-generation sequencing.
The companies will collaborate on developing and optimizing automated protocols for the NimbleGen SeqCap EZ Library solution-based capture method for Caliper's Sciclone NGS Workstation in order to simplify high-throughput targeted resequencing workflows.
Roche and Caliper will develop automated methods for sequencing library preparation and enrichment of target regions, quantification, and quality control, which would enable researchers to analyze large cohorts to discover and confirm genetic variants that may be associated with human disease.
"The continued exponential growth of sequencing throughput and the volume of samples to be analyzed has shifted the bottleneck to sample preparation and process control," Frank Pitzer, CEO of Roche NimbleGen, said in a statement. "By combining our solutions with Caliper's NGS workstation, the bottlenecks are eliminated, creating the capacity to analyze large cohorts and optimize research efforts."
Financial and other terms of the deal were not disclosed.